确定亚细胞组织的物理原理。

Determining physical principles of subcellular organization.

机构信息

School of Engineering and Applied Sciences, Department of Molecular and Cellular Biology, FAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA.

Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany; Max Planck Institute for the Physics of Complex Systems, Nöthnitzerstrasse 38, 01187 Dresden, Germany.

出版信息

Dev Cell. 2014 Apr 28;29(2):135-8. doi: 10.1016/j.devcel.2014.04.018.

DOI:10.1016/j.devcel.2014.04.018

PMID:24780733

Abstract

Recent advances have transformed our understanding of cell biology, but we are still unable to predict the behaviors of these systems. One difficulty is that we lack an understanding of the physical principles of subcellular organization. Combining quantitative experiments with new theoretical insights may allow such principles to be developed.

摘要

近年来的进展改变了我们对细胞生物学的理解，但我们仍然无法预测这些系统的行为。其中一个困难是，我们缺乏对亚细胞组织的物理原理的理解。将定量实验与新的理论见解结合起来，可能会使这些原理得到发展。