Ishii H, Osa Y, Okano T, Isaka S, Yasuda K, Shimazaki J, Komori I, Kodo H, Asano S
Dept. of Urology, School of Medicine, Chiba University.
Gan To Kagaku Ryoho. 1989 Oct;16(10):3483-6.
A patient with stage III testicular cancer was treated by 3 courses of BEP therapy and a partial response was obtained. Afterwards he underwent resection of pulmonary residual tumors and was treated by 2 courses of PE therapy immediately after operation. However, a new pulmonary tumor appeared after the first course of PE therapy was completed. He was treated by high-dose chemotherapy (etoposide 1200 mg/m2, cyclophosphamide 120 mg/kg, CDDP 60 mg/m2) with autologous bone marrow transplantation. Three weeks after high-dose chemotherapy his metastatic pulmonary tumor showed cavity formation which disappeared after 3 months. Fifteen months after the high-dose chemotherapy, no evidence of disease has been seen even without maintenance therapy.
一名III期睾丸癌患者接受了3个疗程的BEP治疗,获得了部分缓解。之后他接受了肺部残留肿瘤切除术,并在术后立即接受了2个疗程的PE治疗。然而,在完成第一个疗程的PE治疗后出现了新的肺部肿瘤。他接受了高剂量化疗(依托泊苷1200 mg/m²、环磷酰胺120 mg/kg、顺铂60 mg/m²)并进行了自体骨髓移植。高剂量化疗3周后,他的转移性肺部肿瘤出现空洞形成,3个月后空洞消失。高剂量化疗15个月后,即使没有维持治疗也未发现疾病迹象。