Błach-Olszewska Z
Laboratory of Infectious Virology, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
Arch Immunol Ther Exp (Warsz). 1988;36(5):511-6.
Natural inhibitor of physiological interferon synthesis (IS-IFN) was tested for its effect on IFN production in various cells isolated from mice. The inhibitor was shown to suppress interferon synthesis in peritoneal cells and partially in bone marrow cells, however, not affecting the level of IFN produced in fibroblasts and leukocytes of peripheral blood. Moreover, peritoneal cells isolated from mice of various inbred lines (Balb/c) NZB and DBA (2) exhibited different sensitivity to the inhibitor effect. The least sensitive appeared cells from NZB mice.
对生理干扰素合成的天然抑制剂（IS-IFN）进行了测试，以观察其对从小鼠分离的各种细胞中干扰素产生的影响。结果显示，该抑制剂可抑制腹膜细胞中的干扰素合成，对骨髓细胞的抑制作用部分存在，然而，它不影响成纤维细胞和外周血白细胞中产生的干扰素水平。此外，从不同近交系（Balb/c、NZB和DBA(2)）小鼠分离的腹膜细胞对该抑制剂的作用表现出不同的敏感性。对该抑制剂最不敏感的是NZB小鼠的细胞。
