Błach-Olszewska Z
Arch Immunol Ther Exp (Warsz). 1986;34(2):225-30.
A suspension of resident peritoneal cells isolated from individual Balb/c mice was subjected to gradual separation into the cells adherent and nonadherent to glass. The isolated fast adherent fraction displayed regulatory properties in relation to spontaneous interferon synthesis. Depending on whether the cells come from strong or weak producers of physiological interferon, they either potentiated or inhibited IFN synthesis. In the former case when fast--adherent cells were removed the suppression of IFN synthesis was observed. Its addition to peritoneal cells producing interferon, increased the titers of interferons obtained. However, when the cells originated from weak producers, exclusion of fast adherent fraction resulted in unblocking of the synthesis of interferon. On the other hand addition of fast adherent fraction to peritoneal cells producing spontaneous IFN caused inhibition of the synthesis.
从个体Balb/c小鼠分离出的腹腔常驻细胞悬液被逐步分离成贴壁细胞和非贴壁细胞。分离出的快速贴壁部分在自发干扰素合成方面表现出调节特性。根据细胞来自生理干扰素的强生产者还是弱生产者，它们要么增强要么抑制干扰素合成。在前一种情况下，当去除快速贴壁细胞时，观察到干扰素合成受到抑制。将其添加到产生干扰素的腹腔细胞中，可提高获得的干扰素滴度。然而，当细胞来自弱生产者时，排除快速贴壁部分会导致干扰素合成的解除抑制。另一方面，将快速贴壁部分添加到产生自发干扰素的腹腔细胞中会导致合成受到抑制。
