Jessen Henning J, Ahmed Nisar, Hofer Alexandre
University of Zürich, Department of Chemistry, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
Org Biomol Chem. 2014 Jun 14;12(22):3526-30. doi: 10.1039/c4ob00478g. Epub 2014 Apr 30.
Esters and anhydrides of phosphoric acid are essential in biology. It is very difficult to identify processes in life that do not involve these modifications and their transformation at some point. Consequently, phosphorylation chemistry is an essential methodology with significant impact on the biological sciences. This perspective gives an overview of some very recent achievements in synthetic phosphorylation chemistry and aims at identifying challenges that lie ahead.
磷酸酯和酸酐在生物学中至关重要。很难确定生命过程中在某个阶段不涉及这些修饰及其转化的情况。因此，磷酸化化学是一种对生物科学有重大影响的重要方法。本文综述了合成磷酸化化学的一些最新成果，并旨在找出未来面临的挑战。
