Reichman David, Rosenwaks Zev
Center of Reproductive Medicine and Infertility, Weill Medical College of Cornell University, New York, NY, USA,
Methods Mol Biol. 2014;1154:289-304. doi: 10.1007/978-1-4939-0659-8_13.
In this chapter we elaborate on the intricacies of employing GnRH antagonists for prevention of the endogenous luteinizing hormone surge during IVF. Several practical aspects of implementing a GnRH antagonist-based stimulation protocol are described; selection of the correct dose, choosing when to start the antagonist, programming of cycle starts, selection of the appropriate gonadotropins, and triggering of final oocyte maturation are elucidated.
在本章中,我们详细阐述了在体外受精过程中使用促性腺激素释放激素(GnRH)拮抗剂来预防内源性促黄体生成素激增的复杂性。描述了实施基于GnRH拮抗剂的刺激方案的几个实际方面;阐明了正确剂量的选择、开始使用拮抗剂的时间、周期开始的安排、合适促性腺激素的选择以及最终卵母细胞成熟的触发。