墨西哥的胃癌研究：一项公共卫生重点工作。
Gastric cancer research in Mexico: a public health priority.
作者信息
Sampieri Clara Luz, Mora Mauricio
机构信息
Clara Luz Sampieri, Instituto de Salud Pública, Universidad Veracruzana, Av. Luis Castelazo Ayala, Col. Industrial Ánimas, 91190 Xalapa, Veracruz, México.
出版信息
World J Gastroenterol. 2014 Apr 28;20(16):4491-502. doi: 10.3748/wjg.v20.i16.4491.
This study aimed review studies conducted on Mexican patients diagnosed with gastric cancer and/or diseases associated with its development, in which at least one Mexican institute has participated, and to assess their contributions to the primary and secondary prevention of this disease. A search of the Medline database was conducted using the following keywords: gastric/stomach cancer, Mexico. Studies of the Mexican population were selected in which at least one Mexican Institute had participated and where the findings could support public policy proposals directed towards the primary or secondary prevention of gastric cancer. Of the 148 studies found in the Medline database, 100 were discarded and 48 were reviewed. According to the analysis presented, these studies were classified as: epidemiology of gastric cancer (5/48); risk factors and protectors relating to gastric cancer (9/48); relationship between Helicobacter pylori and pathologies associated with gastric cancer and the development of the disease (16/48); relationship between the Epstein-Barr virus and pathologies associated with gastric cancer and the development of the disease (3/48); molecular markers for the development of diseases associated with gastric cancer and gastric cancer (15/48). Mexico requires a program for the prevention and control of gastric cancer based on national health indicators. This should be produced by a multidisciplinary committee of experts who can propose actions that are relevant in the current national context. The few studies of gastric cancer conducted on the Mexican population in national institutes highlight the poor connection that currently exists between the scientific community and the health sector in terms of resolving this health issue. Public policies for health research should support projects with findings that can be translated into benefits for the population. This review serves to identify national research groups studying gastric cancer in the Mexican population.
本研究旨在回顾至少有一家墨西哥机构参与的、针对被诊断患有胃癌和/或与其发展相关疾病的墨西哥患者开展的研究，并评估这些研究对该疾病一级和二级预防的贡献。使用以下关键词在Medline数据库中进行了检索：胃癌/ 胃部癌症、墨西哥。选取了至少有一家墨西哥机构参与且研究结果能够支持针对胃癌一级或二级预防的公共政策建议的墨西哥人群研究。在Medline数据库中检索到的148项研究中，100项被剔除，48项被纳入综述。根据所呈现的分析，这些研究被分类为：胃癌流行病学（5/48）；与胃癌相关的危险因素和保护因素（9/48）；幽门螺杆菌与胃癌相关病理及疾病发展之间的关系（16/48）；爱泼斯坦-巴尔病毒与胃癌相关病理及疾病发展之间的关系（3/48）；与胃癌及胃癌相关疾病发展的分子标志物（15/48）。墨西哥需要一个基于国家健康指标的胃癌预防和控制项目。这应由一个多学科专家委员会制定，该委员会能够提出在当前国家背景下相关的行动建议。在国家机构中对墨西哥人群开展的少数胃癌研究凸显了科学界与卫生部门目前在解决这一健康问题方面联系薄弱。卫生研究的公共政策应支持那些研究结果能够转化为民众福祉的项目。本综述有助于识别研究墨西哥人群胃癌的国内研究团队。
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