Liang Yuan Bo, Wang Ning Li, Rong Shi Song, Thomas Ravi
*The Affiliated Eye Hospital, School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou, Zhejiang Province †Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong ‡Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing, China §Queensland Eye Institute, University of Queensland, Qld, Australia.
J Glaucoma. 2015 Aug;24(6):469-73. doi: 10.1097/IJG.0000000000000075.
China has a large burden of primary angle-closure glaucoma (PACG) and the approach to treatment is different from that in most parts of the world. In China, trabeculectomy is a mainstay of initial treatment for PACG and laser peripheral iridotomy is reserved for PAC and PACG with peripheral angle synechiae ≤180 degrees. The greater reduction of and more stable IOP, lower frequency of acute angle closure, decreased progression of peripheral anterior synechia and glaucoma, and the reduction of ocular complications associated with long-term use of glaucoma medications support the use of initial trabeculectomy in PACG without significant lens opacities. Further study is required to determine the indications and effectiveness of initial trabeculectomy for PACG in a developing country setting.
中国原发性闭角型青光眼（PACG）的负担较重，其治疗方法与世界上大多数地区不同。在中国，小梁切除术是PACG初始治疗的主要手段，而激光周边虹膜切开术则适用于周边虹膜粘连≤180度的PAC和PACG。眼压降低幅度更大且更稳定、急性闭角频率更低、周边前粘连和青光眼进展减缓，以及与长期使用青光眼药物相关的眼部并发症减少，这些都支持在没有明显晶状体混浊的PACG中采用初始小梁切除术。需要进一步研究以确定在发展中国家环境下PACG初始小梁切除术的适应症和有效性。
