Vettom L, Pritze S
Lepr Rev. 1989 Sep;60(3):187-96. doi: 10.5935/0305-7518.19890024.
The quality control of skin smears is an important tool in improving the diagnosis of leprosy. We evaluated the skin smears sent to us by 50 laboratory technicians of 29 projects in Asia, Africa and South America. The skin smears were judged according to taking, staining and reading. The correlation was altogether satisfactory. In reading, a low correlation was found in 11% (42 slides) and it was seen that the highest percentage of low correlations was found in the false negative smears. The evaluation of cases with a low correlation leads to the conclusion that using the new WHO classification of 1988 will not reduce the number of incorrectly classified cases. From 42 slides showing a low correlation of their BI results, 7% led to a different classification (paucibacillary instead of multibacillary or vice versa) according to the WHO definition given in 1982, but 8% according to the 1988 WHO definition.
皮肤涂片的质量控制是改善麻风病诊断的一项重要手段。我们评估了亚洲、非洲和南美洲29个项目的50名实验室技术人员送来的皮肤涂片。根据取材、染色和判读对皮肤涂片进行评判。总体相关性令人满意。在判读方面，发现11%（42张涂片）的相关性较低，并且可以看出，假阴性涂片中相关性低的比例最高。对相关性较低病例的评估得出的结论是，采用世界卫生组织1988年的新分类法并不会减少分类错误病例的数量。在42张BI结果相关性较低的涂片中，按照1982年世界卫生组织给出的定义，7%导致了不同的分类（少菌型而非多菌型，反之亦然），但按照1988年世界卫生组织的定义则为8%。
