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麻风病皮肤涂片报告中的实验室间和实验室内差异。

Inter- and intra-laboratory variation in the reporting of skin smears in leprosy.

作者信息

Abraham B, Cariappa A

机构信息

Schieffelin Leprosy Research and Training Center, Karigiri, India.

出版信息

Int J Lepr Other Mycobact Dis. 1991 Mar;59(1):76-81.

PMID:2030318
Abstract

This paper defines the variations in the reporting of skin smears between a base and field laboratory in a leprosy control program. Ten percent of all slides read by the field laboratory in a control area were re-read by the base laboratory. There was almost no variation in the reporting of negative slides, but a variation of 1 + was present in approximately 92% of positive slides. Thus, there was agreement in approximately 8% of positive slides. This paper also defines the variations in the reporting of positive slides under "ideal" conditions by describing the results of a study on intra- and inter-observer variations among technicians at the base laboratory. There was between 45% and 55% agreement within observers and about 36% agreement between observers. The results of both studies are compared. Simple guidelines are derived to monitor the reporting of skin smears in leprosy control programs.

摘要

本文定义了麻风病防治项目中基层实验室与现场实验室在皮肤涂片报告方面的差异。控制区现场实验室所阅全部玻片的10%由基层实验室重新阅片。阴性玻片报告几乎没有差异,但约92%的阳性玻片存在1+的差异。因此,约8%的阳性玻片报告一致。本文还通过描述基层实验室技术人员内部和之间观察者差异的研究结果,定义了“理想”条件下阳性玻片报告的差异。观察者内部的一致性在45%至55%之间,观察者之间的一致性约为36%。对两项研究结果进行了比较。得出了简单的指导方针,以监测麻风病防治项目中皮肤涂片的报告。

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Inter- and intra-laboratory variation in the reporting of skin smears in leprosy.麻风病皮肤涂片报告中的实验室间和实验室内差异。
Int J Lepr Other Mycobact Dis. 1991 Mar;59(1):76-81.
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Iris atrophy in patients with newly diagnosed multibacillary leprosy: at diagnosis, during and after completion of multidrug treatment.新诊断的多菌型麻风患者的虹膜萎缩:在诊断时、多药治疗期间及治疗完成后。
Br J Ophthalmol. 2007 Aug;91(8):1019-22. doi: 10.1136/bjo.2006.107177. Epub 2006 Nov 15.
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Incidence of ocular complications in patients with multibacillary leprosy after completion of a 2 year course of multidrug therapy.
完成两年多药治疗疗程后多菌型麻风患者眼部并发症的发生率
Br J Ophthalmol. 2006 Aug;90(8):949-54. doi: 10.1136/bjo.2006.094870. Epub 2006 May 17.
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Incidence of ocular morbidity among multibacillary leprosy patients during a 2 year course of multidrug therapy.多菌型麻风患者在两年多药治疗过程中的眼部发病率。
Br J Ophthalmol. 2006 May;90(5):568-73. doi: 10.1136/bjo.2005.084913.