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基于不同治疗方法的喉癌患者的治疗期望和生活质量结果

Treatment expectations and quality of life outcomes of patients with laryngeal cancer based on different treatment methods.

作者信息

Kucuk Harun, Kurnaz Senem Cengel, Kutlar Gokhan

机构信息

Department of Otolaryngology Head and Neck Surgery, Batman Regional State Hospital, Batman, Turkey,

出版信息

Eur Arch Otorhinolaryngol. 2015 May;272(5):1245-50. doi: 10.1007/s00405-014-3066-7. Epub 2014 May 1.

DOI:10.1007/s00405-014-3066-7
PMID:24789062
Abstract

The treatment expectations of patients with laryngeal carcinoma and their quality of life after treatment were evaluated. We enrolled patients who were receiving treatment for epidermoid carcinoma of the larynx between January 2011 and January 2012. Their expectations from the treatment were evaluated using the visual analog scale (VAS) prior to and at the end of the treatment. Quality of life was assessed using the EORTC QLQ C 30 and EORTC H&N 35 questionnaires 3 months after completion of the treatment. In addition, the Beck Depression Inventory was used for mood assessment of the patients after treatment. As per the VAS scores pre-treatment, no differences were found between treatment expectations of early and advanced-stage tumors groups in pre-treatment expectations, but post-treatment evaluation statistically found difference between two groups in terms of average VAS score. Emotional, cognitive, and social functions of the EORTC QLQ C 30 questionnaire were the most affected items in the advanced-stage tumor group. Sense and speech problems in the symptom scales of the EORTC H&N 35 questionnaire were found to be significantly higher in patients with advanced-stage tumors than in those with early stage tumors. The present study is the first to assess the treatment expectations of patients with laryngeal carcinoma by using the VAS. Although the treatment expectations of the patients with early and advanced-stage tumors did not differ according to VAS scores in pre-treatment evaluation, early stage groups had better score than advanced-stage group. VAS was an easy and a simple applicable method for evaluating treatment expectations.

摘要

评估了喉癌患者的治疗期望及其治疗后的生活质量。我们纳入了在2011年1月至2012年1月期间接受喉表皮样癌治疗的患者。在治疗前和治疗结束时使用视觉模拟量表(VAS)评估他们对治疗的期望。在治疗完成3个月后,使用欧洲癌症研究与治疗组织(EORTC)QLQ C 30和EORTC H&N 35问卷评估生活质量。此外,使用贝克抑郁量表对患者治疗后的情绪进行评估。根据治疗前的VAS评分,早期和晚期肿瘤组在治疗前的期望方面未发现差异,但治疗后的评估在平均VAS评分方面统计学上发现两组之间存在差异。EORTC QLQ C 30问卷中的情感、认知和社会功能是晚期肿瘤组中受影响最大的项目。EORTC H&N 35问卷症状量表中的感觉和言语问题在晚期肿瘤患者中明显高于早期肿瘤患者。本研究首次使用VAS评估喉癌患者的治疗期望。尽管在治疗前评估中,早期和晚期肿瘤患者的治疗期望根据VAS评分没有差异,但早期组的得分高于晚期组。VAS是一种评估治疗期望的简单易行的方法。

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