T-cell immunity in the aging human.
作者信息
Pawelec Graham
出版信息
Haematologica. 2014 May;99(5):795-7. doi: 10.3324/haematol.2013.094383.
Abstract
摘要
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Haematologica. 2014 May;99(5):795-7. doi: 10.3324/haematol.2013.094383.
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本文引用的文献
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The ageing haematopoietic stem cell compartment.衰老的造血干细胞池。
Nat Rev Immunol. 2013 May;13(5):376-89. doi: 10.1038/nri3433. Epub 2013 Apr 15.
2
Immunosenescence in vertebrates and invertebrates.脊椎动物和无脊椎动物的免疫衰老。
Immun Ageing. 2013 Apr 2;10(1):12. doi: 10.1186/1742-4933-10-12.
3
Cohort profile: The Berlin Aging Study II (BASE-II).队列简介：柏林衰老研究II（BASE-II）。
Int J Epidemiol. 2014 Jun;43(3):703-12. doi: 10.1093/ije/dyt018. Epub 2013 Mar 14.
4
Hallmarks of human "immunosenescence": adaptation or dysregulation?人类“免疫衰老”的特征：适应还是失调？
Immun Ageing. 2012 Jul 25;9(1):15. doi: 10.1186/1742-4933-9-15.
5
Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people.在非常年长的人群中，初始外周血CD8⁺ T细胞比例较低以及体外对人巨细胞病毒蛋白的促炎反应不受抑制与更长的生存期相关。
Age (Dordr). 2013 Aug;35(4):1387-99. doi: 10.1007/s11357-012-9425-7. Epub 2012 Jun 4.
6
Impact of age on T cell signaling: a general defect or specific alterations?年龄对 T 细胞信号转导的影响：是普遍缺陷还是特定改变？
Ageing Res Rev. 2011 Jul;10(3):370-8. doi: 10.1016/j.arr.2010.09.008. Epub 2010 Oct 8.
7
Hallmark features of immunosenescence are absent in familial longevity.免疫衰老的标志性特征在家族性长寿中并不存在。
J Immunol. 2010 Oct 15;185(8):4618-24. doi: 10.4049/jimmunol.1001629. Epub 2010 Sep 20.
8
Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects.幼稚CD4 T细胞寿命随年龄增长而增加有助于T细胞稳态，但也促进功能缺陷的发展。
Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18333-8. doi: 10.1073/pnas.0910139106. Epub 2009 Oct 8.
9
Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals.巨细胞病毒血清阳性对健康个体体内主要淋巴细胞亚群的数量有深远影响。
Clin Exp Immunol. 2009 Mar;155(3):423-32. doi: 10.1111/j.1365-2249.2008.03785.x.
10
Immunosenescence of ageing.衰老的免疫衰老
J Pathol. 2007 Jan;211(2):144-56. doi: 10.1002/path.2104.
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