系统性自身免疫性疾病患者的肝脏受累情况。
Liver involvement in patients with systemic autoimmune diseases.
作者信息
Cojocaru Manole, Cojocaru Inimioara Mihaela, Silosi Isabela, Vrabie Camelia Doina
机构信息
Department of Physiology, Faculty of Medicine, "Titu Maiorescu" University, Centre for Rheumatic Diseases, Bucharest, Romania.
Department of Neurology, "Carol Davila" University of Medicine and Pharmacy, Colentina Clinical Hospital, Bucharest, Romania.
出版信息
Maedica (Bucur). 2013 Sep;8(4):394-7.
Abstract
A wide variety of systemic autoimmune diseases (SAD) affects the liver, and various forms of hepatic involvement have been reported. Patients who have SAD, the abnormal liver function tests might be caused by SAD. In most of these patients, SAD should be treated primary. Liver involvement in SAD is a matter of great clinical challenge evoking several questions upon diagnostic criteria for liver diseases and the presence of overlap syndromes. This review will describe liver injury caused by various systemic autoimmune diseases.
摘要
多种全身性自身免疫性疾病（SAD）会影响肝脏，并且已经报道了各种形式的肝脏受累情况。患有SAD的患者，肝功能检查异常可能由SAD引起。在大多数这些患者中，应首先治疗SAD。SAD中的肝脏受累是一个重大的临床挑战，引发了关于肝病诊断标准和重叠综合征存在的几个问题。本综述将描述由各种全身性自身免疫性疾病引起的肝损伤。
相似文献
1
Liver involvement in patients with systemic autoimmune diseases.
Maedica (Bucur). 2013 Sep;8(4):394-7.
2
The overlap of Sjögren's syndrome with other systemic autoimmune diseases.
Semin Arthritis Rheum. 2007 Feb;36(4):246-55. doi: 10.1016/j.semarthrit.2006.08.007. Epub 2006 Sep 22.
3
Hepatic manifestations in systemic lupus erythematosus.
Lupus. 2020 Jul;29(8):813-824. doi: 10.1177/0961203320923398. Epub 2020 May 9.
4
Connective tissue diseases and the liver.
J Clin Gastroenterol. 2002 Oct;35(4):345-9. doi: 10.1097/00004836-200210000-00012.
5
[Prognostic implications of extra-hepatic clinical manifestations, autoimmunity and microscopic nail capillaroscopy in patients with primary biliary cirrhosis].
Med Clin (Barc). 2016 Jan 1;146(1):8-15. doi: 10.1016/j.medcli.2015.02.026. Epub 2015 May 12.
6
Systemic autoimmune diseases co-existing with chronic hepatitis C virus infection (the HISPAMEC Registry): patterns of clinical and immunological expression in 180 cases.
J Intern Med. 2005 Jun;257(6):549-57. doi: 10.1111/j.1365-2796.2005.01490.x.
7
Systemic autoimmune diseases in patients with hepatitis C virus infection: characterization of 1020 cases (The HISPAMEC Registry).
J Rheumatol. 2009 Jul;36(7):1442-8. doi: 10.3899/jrheum.080874. Epub 2009 Apr 15.
8
Sudden Sensorioneural Hearing Loss and Autoimmune Systemic Diseases.
Int Arch Otorhinolaryngol. 2017 Jul;21(3):213-223. doi: 10.1055/s-0036-1586162. Epub 2016 Jul 26.
9
Liver in systemic disease.
World J Gastroenterol. 2008 Jul 14;14(26):4111-9. doi: 10.3748/wjg.14.4111.
10
Overlap syndromes with autoimmune hepatitis in chronic cholestatic liver diseases.
Expert Rev Gastroenterol Hepatol. 2007 Dec;1(2):329-40. doi: 10.1586/17474124.1.2.329.
引用本文的文献
1
The impact of hydrogen-rich water on liver enzyme levels in clinical populations: a comprehensive review and meta-analysis.
Gastroenterol Hepatol Bed Bench. 2024;17(4):338-348. doi: 10.22037/ghfbb.v17i4.2990.
2
The possible role of Helicobacter pylori in liver diseases.
Arch Microbiol. 2023 Jul 11;205(8):281. doi: 10.1007/s00203-023-03602-z.
3
Anti-inflammatory and Hepatoprotective Effects of Quercetin in an Experimental Model of Rheumatoid Arthritis.
Inflammation. 2021 Oct;44(5):2033-2043. doi: 10.1007/s10753-021-01479-y. Epub 2021 Jun 2.
4
Characterization of the Effect of Hepatic Impairment on Upadacitinib Pharmacokinetics.
J Clin Pharmacol. 2019 Sep;59(9):1188-1194. doi: 10.1002/jcph.1414. Epub 2019 Apr 11.
5
Clinical connection between rheumatoid arthritis and liver damage.
Rheumatol Int. 2018 May;38(5):715-724. doi: 10.1007/s00296-018-4021-5. Epub 2018 Apr 7.
本文引用的文献
1
Liver pathology in collagen vascular disorders highlighting the vascular changes within portal tracts.
Indian J Pathol Microbiol. 2011 Jan-Mar;54(1):25-31. doi: 10.4103/0377-4929.77319.
2
Liver involvement in systemic lupus erythematosus: incidence, clinical course and outcome of lupus hepatitis.
Clin Exp Rheumatol. 2010 Jul-Aug;28(4):504-10. Epub 2010 Aug 30.
3
Risk and management of liver toxicity during methotrexate treatment in rheumatoid and psoriatic arthritis: a systematic review of the literature.
Clin Exp Rheumatol. 2009 Nov-Dec;27(6):1017-25.
4
Elevated liver enzyme tests among patients with rheumatoid arthritis or psoriatic arthritis treated with methotrexate and/or leflunomide.
Ann Rheum Dis. 2010 Jan;69(1):43-7. doi: 10.1136/ard.2008.101378.
5
[The liver and methotrexate].
Gastroenterol Clin Biol. 2008 Feb;32(2):134-42. doi: 10.1016/j.gcb.2007.11.002.
6
Lupus-related advanced liver involvement as the initial presentation of systemic lupus erythematosus.
J Microbiol Immunol Infect. 2006 Dec;39(6):471-5.
7
Systematic review: the hepatotoxicity of non-steroidal anti-inflammatory drugs.
Aliment Pharmacol Ther. 2004 Aug 15;20(4):373-80. doi: 10.1111/j.1365-2036.2004.02092.x.
8
Hepatic manifestations of autoimmune rheumatic diseases.
Ann Rheum Dis. 2004 Aug;63(8):1004-5; discussion 1005.
9
Autoimmune hepatitis accompanied by systemic lupus erythematosus.
Intern Med. 2004 Mar;43(3):258-62. doi: 10.2169/internalmedicine.43.258.
10
Leflunomide for the treatment of rheumatoid arthritis in clinical practice: incidence and severity of hepatotoxicity.
Drug Saf. 2004;27(5):345-52. doi: 10.2165/00002018-200427050-00006.
Zotero 插件