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影响摩洛哥抗哮喘仿制药消费的因素:1999 - 2010年

Factors influencing anti-asthmatic generic drug consumption in Morocco: 1999-2010.

作者信息

Ghanname Imane, Ahid Samir, Berrada Ghizlane, Belaiche Abdelmjid, Hassar Mohammed, Cherrah Yahia

机构信息

Research team of Pharmacoepidemiology & Pharmacoeconomics, Faculty of Medicine and Pharmacy of Rabat. Morocco, University Mohammed V -Souissi, Rabat, Morocco.

Department of marketing, Pharmed, Casablanca, 20 380 Morocco.

出版信息

Springerplus. 2014 Apr 16;3:192. doi: 10.1186/2193-1801-3-192. eCollection 2014.

Abstract

BACKGROUND

The increasing availability of generic drugs (GD) resulted in a remarkable reduction in treatment costs that allowed a better access to health care.The aim of this study is to evaluate the share of anti-asthmatic generic drugs during the period 1999-2010 in Morocco and to look at the factors influencing generic development.

METHODS

In this study, we used Moroccan sales data from IMS Health (Intercontinental Marketing Services). The consumption of the drugs was expressed in DDD/1000 inhabitants/day according to the WHO ATC/DDD methodology.

RESULTS

Between 1999 and 2010, anti-asthmatic consumption increased from 3.91 to 14.43 DDD/1000 inhabitants/day. The market of anti-asthmatic generic drugs progressed from 1.83 (47%) to 2.18 (23%) DDD/1000 inhabitants/day from 1999 to 2010. In 2010, inhaled glucocorticosteroids ranked first (0.83 DDD/1000 inhabitants/day), followed by inhaled short acting beta agonists (0.73 DDD/1000 inhabitants/day). The number of brands went from 27 in 1999 to 34 in 2010, with a generic share increasing from 55.55% to 70.59%. The number of anti-asthmatic pharmaceutical preparations increased from 57 to 64 during the same period, of which 31 and 42 were generic preparations. In 2010, the total cost of anti-asthmatic dugs was about 22 million euro, the generics representing 14 million euro.

CONCLUSION

Despite the introduction of a compulsory insurance scheme called "AMO", that allows a refund for 69.5% of anti-asthmatic specialties marketed in Morocco, anti-asthmatic generic drug consumption remains limited. The Moroccan market is still largely dominated by the originator drugs with still valid patents.

摘要

背景

仿制药(GD)的可获得性不断提高,使得治疗成本显著降低,从而使人们能更好地获得医疗保健服务。本研究的目的是评估1999年至2010年期间摩洛哥抗哮喘仿制药的份额,并探讨影响仿制药发展的因素。

方法

在本研究中,我们使用了艾美仕市场研究公司(IMS Health,洲际营销服务公司)提供的摩洛哥销售数据。根据世界卫生组织的解剖学治疗学化学分类系统/限定日剂量(WHO ATC/DDD)方法,药物消费量以限定日剂量/每千居民/天(DDD/1000 inhabitants/day)表示。

结果

1999年至2010年期间,抗哮喘药物消费量从3.91 DDD/1000居民/天增加到14.43 DDD/1000居民/天。1999年至2010年,抗哮喘仿制药市场从1.83(47%)DDD/1000居民/天增长到2.18(23%)DDD/1000居民/天。2010年,吸入性糖皮质激素排名第一(0.83 DDD/1000居民/天),其次是吸入性短效β受体激动剂(0.73 DDD/1000居民/天)。品牌数量从1999年的27个增加到2010年的34个,仿制药份额从55.55%增加到70.59%。同期,抗哮喘药物制剂数量从57种增加到64种,其中仿制药制剂分别为31种和42种。2010年,抗哮喘药物的总成本约为2200万欧元,仿制药为1400万欧元。

结论

尽管摩洛哥引入了名为“AMO”的强制保险计划,该计划允许对摩洛哥市场上69.5%的抗哮喘专科药物进行报销,但抗哮喘仿制药的消费量仍然有限。摩洛哥市场仍然主要由拥有有效专利的原研药主导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8fc/4002999/e8ae4c373dff/40064_2013_911_Fig1_HTML.jpg

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