Falk Absalom, Afriat Amichay, Hubary Yechiel, Herzog Lior, Eisenkraft Arik
Harefuah. 2014 Mar-Apr;153(3-4):180-3, 238.
Infant botulism is a paralytic syndrome which manifests as a result of ingesting spores of the toxin secreting bacterium Clostridium botulinum by infants. As opposed to botulism in adults, treating infant botulism with horse antiserum was not approved due to several safety issues. This restriction has led to the development of Human Botulism Immune Globulin Intravenous (BIG-IV; sells under BabyBIG). In this article we review infant botulism and the advantages of treating it with BIG-IV.
婴儿肉毒中毒是一种麻痹综合征，是由于婴儿摄入分泌毒素的肉毒梭菌孢子而引起的。与成人肉毒中毒不同，由于一些安全问题，用马抗血清治疗婴儿肉毒中毒未获批准。这种限制促使了静脉注射用人肉毒中毒免疫球蛋白（BIG-IV；商品名为BabyBIG）的研发。在本文中，我们将综述婴儿肉毒中毒以及用BIG-IV治疗该病的优势。
