Pyysalo Mikko, Helminen Mika, Antalainen Anna-Kaisa, Sándor George K, Wolff Jan
Oral and Maxillofacial Unit, Department of Otorhinolaryngology, Tampere University Hospital , Tampere , Finland.
Acta Odontol Scand. 2014 Nov;72(8):806-10. doi: 10.3109/00016357.2014.913194. Epub 2014 May 5.
The peri-operative use of prophylactic antibiotics in clinically healthy patients undergoing dental implant surgery is very common in Finland. While antibiotics are prescribed with the hope of preventing both local and systemic complications, their application and utilization is not uniform.
The aim of this study was to assess the variation in prescribing patterns among Finnish dentists performing dental implant placement operations. This study also aimed to examine the possible relationship between early implant removal and the use of the prophylactic antibiotics in Finland.
The National Institute for Health and Welfare in Finland granted permission to access the Finnish Dental Implant Register. The peri-operative antibiotic prophylaxis prescribing patterns were assessed in a total of 110 543 dental implant placement procedures and 1038 dental implant removal operations performed in Finland between April 1994 and April 2012.
A total of 61 different antibiotics or combinations were prescribed peri-operatively during implant placements in Finland between 1994-2012. Phenoxymethylpenicillin was the most commonly prescribed drug (72.2%). No statistically significant difference in early implant removal rates could be found between patients who had or had not received peri-operative prophylaxis. However, patients who had received peri-operative prophylaxis had statistically significant longer implant survival rates.
There is a variation in antibiotic prescribing patterns among Finnish dentists placing dental implants. The results suggest that the use of prophylactic antibiotics has little effect on the prevention of primary implant surgery-related complications and, hence, success rates.
在芬兰,临床健康的患者接受牙种植手术时围手术期使用预防性抗生素的情况非常普遍。尽管开具抗生素是希望预防局部和全身并发症,但其应用并不统一。
本研究的目的是评估芬兰进行牙种植手术的牙医在开处方模式上的差异。本研究还旨在探讨芬兰早期种植体取出与预防性抗生素使用之间的可能关系。
芬兰国家健康与福利研究所批准访问芬兰牙种植登记册。对1994年4月至2012年4月期间在芬兰进行的总共110543例牙种植手术和1038例牙种植体取出手术的围手术期抗生素预防开处方模式进行了评估。
1994 - 2012年期间,芬兰在种植体植入围手术期共开具了61种不同的抗生素或抗生素组合。苯氧甲基青霉素是最常开具的药物(72.2%)。接受或未接受围手术期预防的患者在早期种植体取出率方面未发现统计学上的显著差异。然而,接受围手术期预防的患者在统计学上有显著更长的种植体生存率。
芬兰进行牙种植的牙医在抗生素开处方模式上存在差异。结果表明,预防性抗生素的使用对预防原发性种植手术相关并发症及成功率影响不大。