Khalil Dalia, Hultin Margareta, Andersson Fred Linda, Parkbring Olsson Nina, Lund Bodil
Department of Dental Medicine, Division of Periodontology, Karolinska Institutet, Huddinge, Sweden.
Swedish Public Dental Service, Stockholm, Sweden.
Clin Oral Implants Res. 2015 Sep;26(9):1064-9. doi: 10.1111/clr.12402. Epub 2014 Apr 15.
To investigate antibiotic prophylaxis prescription behaviors among Swedish dentists working with dental implant surgery and the influence of scientific reviews.
An observational questionnaire study was conducted in 2008 and 2012. Dental clinic addresses were found through online search services of Swedish telephone directories. The questionnaires were posted to eligible dentists (120 in 2008, 161 in 2012) in the Stockholm region, Sweden. Absolute frequencies were used to describe the data. Chi-square tests were applied to assess statistically significant differences.
The response rate was 75% in 2008 and 88% in 2012. In 2008, 88% of the dentists routinely prescribed antibiotic prophylaxis when performing implant surgery and 74% in 2012 (P = 0.01). There was a significant reduction in the dentists prescription patterns as 65% prescribed a single dose in 2012, compared to 49% in 2008 (P = 0.04). Amoxicillin was the drug of choice for 47% of the respondents in 2012, and 21% in 2008 (P = 0.01). Dentists without postgraduate clinical training were significantly more prone to extend antibiotic administration after surgery (P < 0.009).
There is a wide variation in the choice of compound and prescription patterns of prophylactic antibiotic prior to implant insertion. A reduction in antibiotic prescription to a single dose was observed comparing 2008 and 2012, probably influenced by scientific reviews. Dentists with postgraduate education are more likely to limit antibiotic usage.
调查瑞典从事牙种植手术的牙医的抗生素预防用药行为以及科学综述的影响。
在2008年和2012年进行了一项观察性问卷调查研究。通过瑞典电话簿的在线搜索服务找到牙科诊所地址。问卷被寄给瑞典斯德哥尔摩地区符合条件的牙医(2008年120名,2012年161名)。使用绝对频率描述数据。应用卡方检验评估统计学上的显著差异。
2008年的回复率为75%,2012年为88%。2008年,88%的牙医在进行种植手术时常规开具抗生素预防用药,2012年为74%(P = 0.01)。牙医的处方模式有显著减少,因为2012年65%的人开具单剂量处方,而2008年为49%(P = 0.04)。2012年,47%的受访者选择阿莫西林作为药物,2008年为21%(P = 0.01)。未接受研究生临床培训的牙医在手术后显著更倾向于延长抗生素使用时间(P < 0.009)。
在植入种植体前预防性抗生素的复方选择和处方模式存在很大差异。与2008年相比,2012年观察到抗生素处方减少至单剂量,这可能受到科学综述的影响。接受研究生教育的牙医更有可能限制抗生素的使用。