Salgado-Peralvo Angel Orión, Kewalramani Naresh, Peña-Cardelles Juan Francisco, Mateos-Moreno María Victoria, Monsalve-Guil Loreto, Jiménez-Guerra Álvaro, Ortiz-García Iván, Velasco-Ortega Eugenio
Department of Stomatology, University of Seville, 41009 Seville, Spain.
Science Committee for Antibiotic Research of Spanish Society of Implants (SEI-Sociedad Española de Implantes), 28020 Madrid, Spain.
Antibiotics (Basel). 2021 Mar 14;10(3):301. doi: 10.3390/antibiotics10030301.
The prescription of preventive antibiotics (PA) in oral implantology is a controversial issue. The study aimed to determine the prescribing habits of PA in professionals dedicated to oral implantology in various treatments in healthy and at-risk patients. This is a cross-sectional observational study based on the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines. An electronic survey consisting of 4 blocks of questions was sent to members of the Spanish Society of Implants. The data were analyzed using descriptive analysis. A total of 303 participants (20.8%) responded to the questionnaire. One percent never prescribed PA, 55.4% prescribed them always, and 43.6% prescribed them sometimes. Ninety-six percent administered them preoperatively, while 92.4% administered them postoperatively. The most commonly used antibiotic is amoxicillin followed by amoxicillin with clavulanic acid (875/125 mg). Clindamycin is the most commonly administered antibiotic in patients with allergies. Professionals dedicated to oral implantology frequently prescribe PA in both healthy and at-risk patients, especially perioperatively. Immediate implant placement, sinus lifts, bone regeneration, and multiple implant placement are the treatments in which PA are most commonly prescribed, as well as in patients with heart valve prostheses or a history of bacterial endocarditis and immunodeficiency.
口腔种植学中预防性抗生素（PA）的处方是一个有争议的问题。该研究旨在确定致力于口腔种植学的专业人员在健康和有风险患者的各种治疗中使用PA的处方习惯。这是一项基于STROBE（加强流行病学观察性研究报告）指南的横断面观察性研究。一份由4组问题组成的电子调查问卷被发送给西班牙种植学会的成员。使用描述性分析对数据进行分析。共有303名参与者（20.8%）回复了问卷。1%的人从未开具过PA，55.4%的人总是开具PA，43.6%的人有时开具PA。96%的人在术前使用PA，而92.4%的人在术后使用PA。最常用的抗生素是阿莫西林，其次是阿莫西林克拉维酸（875/125毫克）。克林霉素是过敏患者中最常用的抗生素。致力于口腔种植学的专业人员在健康和有风险的患者中都经常开具PA，尤其是在围手术期。即刻种植、上颌窦提升、骨再生和多颗种植体植入是最常开具PA的治疗方式，以及患有心脏瓣膜假体或有细菌性心内膜炎和免疫缺陷病史的患者。
