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蕈样肉芽肿多药联合化疗方案疗效的比较评估

[Comparative evaluation of the efficacy of polychemotherapeutic combinations in mycosis fungoides].

作者信息

Kutasevich Ia F

出版信息

Vestn Dermatol Venerol. 1989(8):48-53.

PMID:2479189
Abstract

Comparative assessment of the efficacies of several chemotherapeutic complexes permit recommending the following complexes for the treatment of mycosis fungoides: prospidin-vincristine-prednisolone, cyclophosphamide-vincristine-prednisolone, cyclophosphamide-vincristine-bleomycin-prednisolone, in doses and schemes suggested by the author. The first complex is more sparing and is recommended for elderly patients with concomitant diseases and initially depressed hemopoiesis. The second and third complexes are characterized by more intensive action and help achieve a clinical remission even in cases with significant involvement.

摘要

对几种化疗组合疗效的比较评估使得可以推荐以下组合用于蕈样肉芽肿的治疗

作者建议剂量和方案的丙酰螺旋霉素 - 长春新碱 - 泼尼松龙、环磷酰胺 - 长春新碱 - 泼尼松龙、环磷酰胺 - 长春新碱 - 博来霉素 - 泼尼松龙。第一种组合副作用较小,推荐用于伴有其他疾病且初始造血功能低下的老年患者。第二种和第三种组合作用更强,即使在病情严重的情况下也有助于实现临床缓解。

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