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减少复苏液用量对10%-20%体表面积烫伤儿童预后的影响

Impact of reduced resuscitation fluid on outcomes of children with 10-20% body surface area scalds.

作者信息

Walker T L J, Rodriguez D Urriza, Coy K, Hollén L I, Greenwood R, Young A E R

机构信息

Frenchay Hospital, North Bristol NHS Trust, United Kingdom.

University of Bristol, United Kingdom.

出版信息

Burns. 2014 Dec;40(8):1581-6. doi: 10.1016/j.burns.2014.02.013. Epub 2014 May 1.

Abstract

'Permissive hypovolaemia' fluid regimes in adult burn care are suggested to improve outcomes. Effects in paediatric burn care are less well understood. In a retrospective audit, outcomes of children from the South West Children's Burn Centre (SWCBC) less than 16 years of age with scalds of 10-20% burn surface area (BSA) managed with a reduced volume fluid resuscitation regime (post-2007) were compared to (a) an historical local protocol (pre-2007) and (b) current regimes in burn services across England and Wales (E&W). Outcomes included length of stay per percent burn surface area (LOS/%BSA), skin graft requirement and re-admission rates. 92 SWCBC patients and 475 patients treated in 15 other E&W burn services were included. Median LOS/%BSA for patients managed with the reduced fluid regime was 0.27 days: significantly less than pre-2007 and other E&W burn services (0.54 days, 0.50 days, p<0.001). Skin grafting to achieve healing reduced post-2007 compared to pre-2007 and remains comparable with other E&W services. Re-admission rates were comparable between all groups. A reduced fluid regime has significantly shortened LOS/%BSA without compromising burn depth as measured by skin grafting to achieve healing. A prospective trial comparing permissive hypovolaemia to current regimes for moderate paediatric scald injuries would help clarify.

摘要

成人烧伤护理中采用“允许性低血容量”液体治疗方案被认为可改善治疗效果。而其在小儿烧伤护理中的效果尚不太清楚。在一项回顾性审计中,将西南儿童烧伤中心(SWCBC)16岁以下、烧伤表面积(BSA)为10%-20%的烫伤患儿采用减少液体复苏量治疗方案(2007年后)的治疗效果,与(a)当地历史治疗方案(2007年前)以及(b)英格兰和威尔士(E&W)各地烧伤服务机构的现行治疗方案进行了比较。治疗效果包括每百分比烧伤表面积的住院时间(LOS/%BSA)、皮肤移植需求和再入院率。研究纳入了92名SWCBC患者以及在其他15家E&W烧伤服务机构接受治疗的475名患者。采用减少液体量治疗方案的患者的中位LOS/%BSA为0.27天:显著低于2007年前以及其他E&W烧伤服务机构(分别为0.54天、0.50天,p<0.001)。与2007年前相比,2007年后为实现愈合而进行皮肤移植的情况有所减少,且与其他E&W服务机构的情况相当。所有组之间的再入院率相当。减少液体量治疗方案显著缩短了LOS/%BSA,且在通过皮肤移植实现愈合来衡量烧伤深度方面没有受到影响。一项比较允许性低血容量与现行方案治疗中度小儿烫伤的前瞻性试验将有助于阐明这一问题。

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