Almeida Prado Oliveira e Sousa Maria Luiza, de Oliveira Marco Aurelio Tuena, Auler-Bittencout Eloisa A, Soares-Vieira Jose Arnaldo, Munoz Daniel Romero, Iwamura Edna Sadayo Miazato
Laboratório de Patologia Molecular- Escola Paulista de Medicina-Universidade Federal de São Paulo EPM/UNIFESP, Rua Botucatu 740, Vila Clementino, 04023-062 São Paulo, SP, Brazil; Laboratório de DNA, Núcleo de Biologia e Bioquímica, Instituto de Criminalística de São Paulo, Rua Moncorvo Filho, 410, 05507-060 São Paulo, SP, Brazil.
Laboratório de Patologia Molecular- Escola Paulista de Medicina-Universidade Federal de São Paulo EPM/UNIFESP, Rua Botucatu 740, Vila Clementino, 04023-062 São Paulo, SP, Brazil.
Forensic Sci Int Genet. 2014 Jul;11:e15-7. doi: 10.1016/j.fsigen.2014.03.018. Epub 2014 Apr 12.
The State of São Paulo is the most populous state in Brazil, including approximately one fifth of the population of the country. In addition to a strong economy, the state has relatively good social indicators when compared with the rest of the country. The capital city, also called São Paulo, is the sixth largest city in the world. Its population is considered the most multicultural and racially mixed in Brazil. Currently, the largest populations in São Paulo are of Italian, Lebanese, Spanish and Japanese origin, and the state has the largest number of Northeasterners outside of the Northeast region. This population structure may lead to a particular genotype frequency. In this context, the formation of a new database containing the allele frequencies of five new genetic markers (D2S441, D10S1248, D22S1045, D1S1656 and D12S391) in a sample population is relevant. The allele frequencies of 16 STR loci, including the five new European Standard Set (ESS) loci, were calculated in a sample of 1088-1098 unrelated individuals, who geographically represent the Capital city.
圣保罗州是巴西人口最多的州，约占全国人口的五分之一。除了经济强劲外，与巴西其他地区相比，该州的社会指标也相对较好。其首府也叫圣保罗，是世界第六大城市。其人口被认为是巴西最多元文化和种族混合的。目前，圣保罗州人口中意大利、黎巴嫩、西班牙和日本裔占比最大，且该州拥有东北地区以外数量最多的东北部人。这种人口结构可能导致特定的基因型频率。在此背景下，在一个样本群体中形成一个包含五个新遗传标记（D2S441、D10S1248、D22S1045、D1S1656和D12S391）等位基因频率的新数据库具有重要意义。在1088 - 1098名无亲缘关系个体的样本中计算了16个STR位点的等位基因频率，这些个体在地理上代表了首府城市。
