Neumann Roxann M, Garvey Colleen, Kaufman Sharon
Semin Oncol Nurs. 2014 May;30(2):117-23. doi: 10.1016/j.soncn.2014.03.005.
To provide an overview of emerging applications for and challenges associated with biospecimen collection for evaluating personalized disease risk and/or treatment response in cancer clinical trials.
Published nursing and medical literature.
Blood- and tissue-based biomarkers are increasingly utilized to identify the molecular signatures of disease that can inform the determination of a course of treatment in a very precise manner. There are challenges for the oncology nurse related to specimen collection, processing, analysis, and translation to precision treatment.
It is important for nurses to have appropriate training and a working understanding of the procedures for biospecimen collection and how biospecimen analyses can inform precision assessment of risk and prognosis.
概述生物样本采集在癌症临床试验中评估个性化疾病风险和/或治疗反应方面的新兴应用及相关挑战。
已发表的护理和医学文献。
基于血液和组织的生物标志物越来越多地用于识别疾病的分子特征，从而能够非常精确地为治疗方案的确定提供依据。肿瘤护理人员在样本采集、处理、分析以及转化为精准治疗方面面临挑战。
护士接受适当培训并切实了解生物样本采集程序以及生物样本分析如何为风险和预后的精准评估提供依据非常重要。
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