Zou Donghua, Shao Yu, Qin Zhiqiang, Zhang Jianhua, Liu Ningguo, Li Zhengdong, Huang Ping, Chen Yijiu
Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, 1347 West Guangfu Road, Shanghai 200063, PR China.
J Forensic Leg Med. 2014 May;24:12-4. doi: 10.1016/j.jflm.2014.02.011. Epub 2014 Mar 6.
The paper reports on a rare case of fulminant neuroleptic malignant syndrome (NMS) with several risk factors, typical manifestation and rapid death induced by low doses of haloperidol. The pathological findings, pathogenesis, clinical manifestations, diagnostic criteria, risk factors and other features of NMS are discussed. The importance of forensic pathologists being aware of the possibility of NMS as the cause of death in people taking antipsychotic drugs is stressed.
本文报道了一例罕见的暴发性抗精神病药物恶性综合征（NMS），该病例存在多种危险因素，有典型表现，并由低剂量氟哌啶醇诱发快速死亡。文中讨论了NMS的病理发现、发病机制、临床表现、诊断标准、危险因素及其他特征。强调了法医病理学家了解NMS作为服用抗精神病药物者死因可能性的重要性。
