Altman S, Baer M F, Bartkiewicz M, Gold H, Guerrier-Takada C, Kirsebom L A, Lumelsky N, Peck K
Department of Biology, Yale University, New Haven, CT 06520.
Gene. 1989 Oct 15;82(1):63-4. doi: 10.1016/0378-1119(89)90030-9.
RNase P, an enzyme that contains both RNA and protein components, cleaves tRNA precursors to generate mature 5' termini. The catalytic activity of RNase P resides in the RNA component, with the protein cofactor affecting the rate of the cleavage reaction. The reaction is also influenced by the nature of the tRNA substrate.