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2
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本文引用的文献

1
Liquid-containing Refluxes and Acid Refluxes May Be Less Frequent in the Japanese Population Than in Other Populations: Normal Values of 24- hour Esophageal Impedance and pH Monitoring.与其他人群相比,含液体反流和酸反流在日本人群中可能不太常见:24小时食管阻抗和pH监测的正常值。
J Neurogastroenterol Motil. 2016 Oct 30;22(4):620-629. doi: 10.5056/jnm15195.
2
Emergent diagnostic testing for pediatric nonfebrile seizures.小儿非热性惊厥的急诊诊断检测
Am J Emerg Med. 2015 Sep;33(9):1261-4. doi: 10.1016/j.ajem.2015.06.004. Epub 2015 Jun 6.
3
Multichannel intraesophageal impedance pattern of children with aerophagia.吞气症患儿的多通道食管内阻抗模式
Neurogastroenterol Motil. 2014 Jul;26(7):1010-4. doi: 10.1111/nmo.12355. Epub 2014 May 5.
4
The gastric accommodation response to meal intake determines the occurrence of transient lower esophageal sphincter relaxations and reflux events in patients with gastro-esophageal reflux disease.胃对进餐的适应性反应决定了胃食管反流病患者一过性下食管括约肌松弛和反流事件的发生。
Neurogastroenterol Motil. 2014 Apr;26(4):581-8. doi: 10.1111/nmo.12305. Epub 2014 Feb 7.
5
Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN).小儿胃食管反流临床实践指南:北美小儿胃肠病学、肝病学和营养学学会(NASPGHAN)和欧洲小儿胃肠病学、肝病学和营养学学会(ESPGHAN)的联合建议。
J Pediatr Gastroenterol Nutr. 2009 Oct;49(4):498-547. doi: 10.1097/MPG.0b013e3181b7f563.
6
Aerophagia: excessive air swallowing demonstrated by esophageal impedance monitoring.吞气症:通过食管阻抗监测证实的过度吞气。
Clin Gastroenterol Hepatol. 2009 Oct;7(10):1127-9. doi: 10.1016/j.cgh.2009.06.029. Epub 2009 Aug 9.
7
Characterization of intraluminal impedance patterns associated with gas reflux in healthy volunteers.健康志愿者中与气体反流相关的腔内阻抗模式的特征分析。
Neurogastroenterol Motil. 2009 Aug;21(8):825-e55. doi: 10.1111/j.1365-2982.2009.01289.x. Epub 2009 Mar 12.
8
Presence of gas in the refluxate enhances reflux perception in non-erosive patients with physiological acid exposure of the oesophagus.反流物中存在气体可增强食管生理性酸暴露的非糜烂性患者的反流感知。
Gut. 2008 Apr;57(4):443-7. doi: 10.1136/gut.2007.130104. Epub 2007 Aug 31.
9
Normal values and day-to-day variability of 24-h ambulatory oesophageal impedance-pH monitoring in a Belgian-French cohort of healthy subjects.比利时-法国健康受试者队列中24小时动态食管阻抗-pH监测的正常值及日常变异性
Aliment Pharmacol Ther. 2005 Nov 15;22(10):1011-21. doi: 10.1111/j.1365-2036.2005.02677.x.
10
Aerophagia, gastric, and supragastric belching: a study using intraluminal electrical impedance monitoring.吞气症、胃气和胃上嗳气:一项使用腔内电阻抗监测的研究
Gut. 2004 Nov;53(11):1561-5. doi: 10.1136/gut.2004.042945.

食管酸暴露正常的儿童中的气体反流

Gas Reflux in Children with Normal Acid Exposure of the Oesofagus.

作者信息

Galos Felicia, Boboc Catalin, Balgradean Mihaela

机构信息

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; "Marie Curie" Emergency Children's Hospital Bucharest, Romania.

"Marie Curie" Emergency Children's Hospital Bucharest, Romania.

出版信息

Maedica (Bucur). 2016 Dec;11(4):345-348.

PMID:28828055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5543530/
Abstract

The clinical manifestations of non-erosive gastroesophageal reflux disease (NERD) are multiple and heterogeneous, and differ according to age and individual susceptibility. Weakly acidic reflux and the presence of gas in the refluxate could be relevant in the pathogenesis of symptoms. We present the case of a 3-year and 5-month-old child who came to the hospital with recurrent paroxysmal manifestations without fever assessed. The positive diagnosis was made using pH-metry associated with multichannel intraluminal impedance and glucose respiratory breath test, a new technique that allows positive diagnosis as well as establishes important connections regarding gas reflux and clinical symptomatology described by the patient.

摘要

非糜烂性胃食管反流病(NERD)的临床表现多样且异质性强,会因年龄和个体易感性而有所不同。弱酸性反流以及反流物中存在气体可能与症状的发病机制有关。我们报告一例3岁5个月大的儿童,该患儿因反复出现无发热的阵发性表现前来就诊。通过pH值测定结合多通道腔内阻抗和葡萄糖呼吸试验做出了阳性诊断,这是一项新技术,不仅能做出阳性诊断,还能建立有关气体反流与患者描述的临床症状之间的重要联系。