Mutalib Mohamed, Rawat David, Lindley Keith, Borrelli Osvaldo, Perring Steve, Auth Marcus K H, Thapar Nikhil
Paediatric Gastroenterology Department, Evelina London Children's Hospital, London, UK.
Paediatric Gastroenterology Department, Royal London Hospital, London, UK.
Frontline Gastroenterol. 2017 Jul;8(3):156-162. doi: 10.1136/flgastro-2016-100796. Epub 2017 Mar 15.
Combined pH-impedance monitoring has been suggested as the investigation of choice for diagnosing gastro-oesophageal reflux in children. Although it is superior to oesophageal pH monitoring in detecting all types of reflux episodes (acid, weakly acidic and alkaline) with the ability to evaluate symptom association with reflux events, it is still limited by the lack of true paediatric normal value and the high cost involved (equipment and personnel).
To produce a position statement on behalf of the Motility Working Group of the British Society of Paediatric Gastroenterology, Hepatology and Nutrition on the indications and practical application of combined oesophageal pH-impedance monitoring in children.
Up-to-date review of available evidence.
This document provides a practical guide to clinician on indications, methods and results interpretation of paediatric multichannel intraluminal impedance pH (MII-pH).
MII-pH is increasingly used by paediatricians as the diagnostic tool for assessing gastro-oesophageal reflux disease and symptom association. There is wide variation in paediatric practice and a need for standardised practice.
联合pH阻抗监测已被推荐为诊断儿童胃食管反流的首选检查方法。尽管它在检测所有类型的反流事件（酸性、弱酸性和碱性）以及评估症状与反流事件的相关性方面优于食管pH监测，但它仍然受到缺乏真正的儿科正常值以及相关成本高昂（设备和人员）的限制。
代表英国儿科学会胃肠病学、肝病学和营养运动工作组就联合食管pH阻抗监测在儿童中的适应证和实际应用发表一份立场声明。
对现有证据进行最新综述。
本文档为临床医生提供了关于儿科多通道腔内阻抗pH（MII-pH）监测的适应证、方法和结果解读的实用指南。
儿科医生越来越多地将MII-pH用作评估胃食管反流病和症状相关性的诊断工具。儿科实践存在很大差异，需要标准化的实践。
