Guo Jingjing, Xiao Yi, Huang Rong, Zhong Xu
Department of Respiratory and Sleep Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2014 Feb;37(2):89-94.
To determine whether slow eye movement (SEM) analysis performed comparably to standard sleep onset criteria at the multiple sleep latency test (MSLT) and the maintenance of wakefulness test (MWT) in patients with obstructive sleep apnea/hyponea syndrome (OSAHS).
We compared SEM latencies with sleep latencies upon analysis of MSLT and MWT recordings artificially, in a population of 20 severe OSAHS patients that randomly underwent the 2 tests 2 days apart. They all answered the Epworth Sleepiness Scale.
Mean SEM latency was different from standard sleep onset in the MSLT [(4.2 ± 1.9) min vs (5.3 ± 2.0) min, P < 0.001], and the MWT [(12 ± 10) min vs (13 ± 10) min, P < 0.001]. Mean SEM latency correlated significantly with the sleep latency at the MSLT (r = 0.958, P < 0.001) and at the MWT (r = 0.997, P < 0.001). Finally, the Epworth Sleepiness Scale score correlated with SEM latency at the MSLT (r = -0.580, P = 0.007), but not at the MWT.
SEM latency was different from sleep latency that detected from EEG, but they correlated significantly with each other, thus providing a simplified way to evaluate sleepiness.
确定在阻塞性睡眠呼吸暂停/低通气综合征（OSAHS）患者中，多导睡眠图睡眠潜伏期试验（MSLT）和清醒维持试验（MWT）时，慢眼动（SEM）分析与标准睡眠起始标准的表现是否相当。
我们对20例重度OSAHS患者进行人工分析MSLT和MWT记录，比较SEM潜伏期与睡眠潜伏期。这些患者随机在间隔2天的时间里分别接受这两项测试。他们都完成了爱泼华嗜睡量表（Epworth Sleepiness Scale）测试。
在MSLT中，平均SEM潜伏期与标准睡眠起始不同[（4.2±1.9）分钟对（5.3±2.0）分钟，P<0.001]，在MWT中也是如此[（12±10）分钟对（13±10）分钟，P<0.001]。平均SEM潜伏期与MSLT时的睡眠潜伏期显著相关（r = 0.958，P<0.001），与MWT时的睡眠潜伏期也显著相关（r = 0.997，P<0.001）。最后，爱泼华嗜睡量表评分与MSLT时的SEM潜伏期相关（r = -0.580，P = 0.007），但与MWT时的SEM潜伏期不相关。
SEM潜伏期与脑电图检测到的睡眠潜伏期不同，但二者显著相关，从而提供了一种评估嗜睡程度的简化方法。
