Putzer David, Coraça-Huber Debora, Wurm Alexander, Schmoelz Werner, Nogler Michael
Experimental Orthopaedics, Department of Orthopaedics, Innsbruck Medical University, Innrain 36, 6020, Innsbruck, Austria.
J Orthop Res. 2014 Aug;32(8):1024-9. doi: 10.1002/jor.22635. Epub 2014 May 5.
In bone impaction grafting, allografts in the form of bone chips are used for reconstruction of defects and to induce bone remodeling. Optimizing grain size distribution of this allograft material should help prevent implant subsidence by achieving higher primary stability of the graft. We evaluated the influence of grain size distribution on the mechanical stability of allograft material. Bone tissue was rinsed, and the grain size distribution of the allograft material was determined by performing a sieve analysis. Uniaxial compression tests were carried out before and after a standardized compaction procedure for samples with controlled grain size distribution and a control group. Allografts with controlled grain size distribution showed a yield limit almost twice as high as in the control group after a standardized compaction procedure. A better interlocking between bone particles was observed compared to the control group. Thus, grain size distribution has a major impact on the mechanical stability of bone grafts. By controlling the grain size distribution of allograft material, a tighter packing can be achieved and subsequently implant subsidence of implants could be avoided.
在骨打压植骨术中，骨屑形式的同种异体骨用于缺损修复和诱导骨重塑。优化这种同种异体骨材料的粒度分布应有助于通过实现更高的移植物初始稳定性来防止植入物下沉。我们评估了粒度分布对同种异体骨材料力学稳定性的影响。冲洗骨组织，并通过筛分分析确定同种异体骨材料的粒度分布。对具有可控粒度分布的样本和一个对照组在标准化压实程序前后进行单轴压缩试验。经过标准化压实程序后，具有可控粒度分布的同种异体骨的屈服极限几乎是对照组的两倍。与对照组相比，观察到骨颗粒之间的嵌合更好。因此，粒度分布对骨移植的力学稳定性有重大影响。通过控制同种异体骨材料的粒度分布，可以实现更紧密的填充，进而避免植入物的下沉。
