Bonnet R, Bertin H, Delemazure A S, Clairand R, Mercier J, Corre P
Clinique de chirurgie maxillo-faciale et de stomatologie, centre hospitalier universitaire de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes, France.
Service d'imagerie médicale, centre hospitalier universitaire de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes, France.
Rev Stomatol Chir Maxillofac Chir Orale. 2014 Jun;115(3):188-91. doi: 10.1016/j.revsto.2014.03.006. Epub 2014 May 3.
Churg-Strauss syndrome is a rare systemic vascularitis. This disease causes eosinophilic tissue infiltration. The most frequent manifestations are cortico-dependent asthma, mono- or polyneuropathy, paranasal sinus polyposis, and digestive and renal dysfunction. Salivary glands are very rarely involved.
We describe a case of CSS in a patient presenting with bilateral parotid swelling. The morphological study of salivary glands revealed an unusual thickening of the salivary duct walls.
Salivary gland involvement in Churg and Strauss syndrome can be difficult to demonstrate histologically; it does not usually present in the clinical foreground of the disease, and can be a source of misdiagnosis. The biopsy should be performed in the symptomatic gland, away from any previous corticoid treatment.
变应性肉芽肿性血管炎是一种罕见的系统性血管炎。这种疾病会导致嗜酸性粒细胞组织浸润。最常见的表现是皮质激素依赖型哮喘、单神经或多神经病、鼻旁窦息肉病以及消化和肾功能障碍。唾液腺极少受累。
我们描述了一例以双侧腮腺肿大为表现的变应性肉芽肿性血管炎患者。唾液腺的形态学研究显示唾液腺导管壁出现异常增厚。
变应性肉芽肿性血管炎累及唾液腺在组织学上可能难以证实；它通常不出现在该疾病的临床主要表现中，并且可能是误诊的一个原因。活检应在有症状的腺体进行，且要远离之前的任何皮质类固醇治疗。
