Ameli F, Phang K S, Masir N
Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Cheras, Kuala Lumpur 56000, Malaysia.
Med J Malaysia. 2011 Dec;66(5):517-9.
Churg-Strauss syndrome, a small and medium vessel vasculitis, was first described by Churg and Strauss in 1951. It is characterised by the presence of asthma, prominent tissue and blood eosinophilia, systemic vasculitis, and pulmonary and systemic necrotising allergic granulomas. Involvement of the skin, heart and gastrointestinal tract is well documented, but ocular presentation is unusual. We describe a 40-year-old lady who presented with recurrent upper eyelid swelling due to conjunctival lesions. Although she has chronic asthma, Churg-Strauss syndrome was never suspected. The diagnosis of Churg-Strauss syndrome was only made following histological examination of the conjunctival lesions.
变应性肉芽肿性血管炎,一种中小血管血管炎,于1951年由Churg和Strauss首次描述。其特征为存在哮喘、显著的组织和血液嗜酸性粒细胞增多、系统性血管炎以及肺部和系统性坏死性过敏性肉芽肿。皮肤、心脏和胃肠道受累已有充分记录,但眼部表现并不常见。我们描述一位40岁女性,因结膜病变出现复发性上睑肿胀。尽管她患有慢性哮喘,但从未怀疑过变应性肉芽肿性血管炎。变应性肉芽肿性血管炎的诊断是在对结膜病变进行组织学检查后才得以确立。