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我们对自闭症谱系障碍中的自杀倾向了解多少?一项系统综述。

What do we know about suicidality in autism spectrum disorders? A systematic review.

作者信息

Segers Magali, Rawana Jennine

机构信息

Department of Psychology, York University, ON, Canada.

出版信息

Autism Res. 2014 Aug;7(4):507-21. doi: 10.1002/aur.1375. Epub 2014 May 5.

Abstract

Suicidality is a common and concerning issue across development, and there is a plethora of research on this topic among typically developing children and youth. Very little is known, however, about the nature of suicidality among individuals with autism spectrum disorders (ASDs). The purpose of the current study was to undertake a systematic literature review to assess the current state of the research literature to examine the prevalence of suicidality among individuals with ASD, related demographic and clinical profiles, and associated risk and protective factors. A literature search using key terms related to suicidality and ASD yielded 10 topical studies that were evaluated for the study objectives. Suicidality was present in 10.9-50% of the ASD samples identified in the systematic review. Further, several large-scale studies found that individuals with ASD comprised 7.3-15% of suicidal populations, a substantial subgroup. Risk factors were identified and included peer victimization, behavioral problems, being Black or Hispanic, being male, lower socioeconomic status, and lower level of education. Only one study reported on protective factors, and this is identified as a significant gap in the literature. Several methodological weaknesses were present in the current literature, such as lack of appropriate comparison groups and little to no use of empirically validated measures for ASD diagnosis and suicide assessment. Additional research is necessary to understand better how this unique population experiences and expresses suicidal tendencies. Recommendations for future research are discussed.

摘要

自杀倾向是贯穿整个成长过程的一个常见且令人担忧的问题,关于这个主题,在发育正常的儿童和青少年中有大量研究。然而,对于自闭症谱系障碍(ASD)患者的自杀倾向本质,我们知之甚少。本研究的目的是进行一项系统的文献综述,以评估研究文献的现状,考察ASD患者自杀倾向的患病率、相关的人口统计学和临床特征,以及相关的风险和保护因素。使用与自杀倾向和ASD相关的关键词进行文献检索,得到了10项专题研究,并根据研究目标进行了评估。在系统综述中确定的ASD样本中,10.9%-50%存在自杀倾向。此外,几项大规模研究发现,ASD患者占自杀人群的7.3%-15%,是一个相当大的亚组。已确定的风险因素包括同伴受害、行为问题、黑人或西班牙裔、男性、社会经济地位较低以及教育水平较低。只有一项研究报告了保护因素,这被认为是文献中的一个重大空白。当前文献存在若干方法学上的弱点,例如缺乏适当的对照组,以及几乎没有使用经过实证验证的ASD诊断和自杀评估措施。有必要进行更多研究,以更好地了解这一独特人群如何体验和表达自杀倾向。文中讨论了对未来研究的建议。

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