Campbell Janis E, Martinez Sydney A, Janitz Amanda E, Pate Anne E, Erb-Alvarez Julie, Wharton David F, Gahn David, Tall Vicki L, Snider Cuyler, Anderson Tom, Peercy Michael
J Okla State Med Assoc. 2014 Mar;107(3):99-107.
This study describes overall and site specific cancer incidence among AI/ANs compared to whites in Oklahoma and differences in cancer staging.
Age-adjusted incidence rates obtained from the Oklahoma Central Cancer Registry are presented for all cancer sites combined and for the most common cancer sites among AI/ANs with comparisons to whites. Percentages of late stage cancers for breast, colorectal, and melanoma cancers are also presented.
AI/ANs had a significantly higher overall cancer incidence rate compared to whites (629.8/100,000 vs. 503.3/100,000), with a rate ratio of 1.25 (95% CI: 1.22, 1.28). There was a significant disparity in the percentage of late stage melanoma cancers between 2005 and 2009, with 14.0% late stage melanoma for whites and 20.0% for AI/ANs (p-value:0.03).
Overall, there were cancer disparities between AI/ANs and whites in Oklahoma. Incidence rates were higher among AI/ANs for all cancers and many site specific cancers.
本研究描述了俄克拉荷马州美国印第安人和阿拉斯加原住民（AI/ANs）与白人相比的总体癌症发病率及特定部位癌症发病率，以及癌症分期的差异。
呈现从俄克拉荷马州中央癌症登记处获得的年龄调整发病率，包括所有癌症部位合并的情况以及AI/ANs中最常见癌症部位的情况，并与白人进行比较。还列出了乳腺癌、结直肠癌和黑色素瘤晚期癌症的百分比。
与白人相比，AI/ANs的总体癌症发病率显著更高（629.8/100,000对503.3/100,000），率比为1.25（95%可信区间：1.22，1.28）。2005年至2009年期间，晚期黑色素瘤癌症的百分比存在显著差异，白人的晚期黑色素瘤为14.0%，AI/ANs为20.0%（p值：0.03）。
总体而言，俄克拉荷马州的AI/ANs和白人之间存在癌症差异。AI/ANs所有癌症及许多特定部位癌症的发病率更高。
