Domján Zsolt, Holman Endre, Bordás Noémi, Dákay Alexander Stephan, Bahrehmand Kiarash, Buzogány István
Department of Urology, Péterfy Sándor Hospital, Péterfy Sándor Str. 8-20, Budapest, 1074, Hungary,
Int Urol Nephrol. 2014 Sep;46(9):1757-60. doi: 10.1007/s11255-014-0726-x. Epub 2014 May 7.
To demonstrate the beneficial results of hand-assisted laparoscopic tumor nephrectomy in pregnancy and to emphasize the proper timing of such surgery for its crucial importance attempting to avoid fatal cancer-related outcomes as a result of late interventions of aggressive tumors.
A report of a 32-year-old woman with a 61 × 41 mm chromophobe renal cell carcinoma (RCC) successfully treated with laparoscopic transperitoneal hand-assisted nephrectomy during the 20th week of gestation is presented.
The fetus was stable during the intervention; the postoperative period was uneventful; she had a normal vaginal delivery at term and gave birth to a healthy female child. The patient remained tumor-free at her 34-month follow-up.
Although the pure laparoscopic interventions have become recognized in the treatment of RCC over the last decade, these methods have their limitations and dangers as well. The hand-assistance method makes the procedure faster and safer which is especially important during second or third trimester. Renal biopsy may play a specifically important role in predicting the malignant potential of a renal tumor, whereas postponement of this surgery until after delivery, may lead to the mother's death. To our knowledge, this is the first report on hand-assisted laparoscopic nephrectomy in pregnancy.
证明手辅助腹腔镜肿瘤肾切除术在妊娠期的有益效果,并强调此类手术的恰当时机至关重要,因为要避免因侵袭性肿瘤的延迟干预而导致致命的癌症相关后果。
报告一名32岁女性,在妊娠第20周时经腹腔镜经腹手辅助肾切除术成功治疗了一例61×41mm的嫌色肾细胞癌(RCC)。
干预期间胎儿稳定;术后过程顺利;她足月顺产,生下一名健康女婴。患者在34个月的随访中无肿瘤复发。
尽管在过去十年中,单纯腹腔镜手术已被认可用于治疗RCC,但这些方法也有其局限性和风险。手辅助方法使手术更快、更安全,这在妊娠中期或晚期尤为重要。肾活检在预测肾肿瘤的恶性潜能方面可能发挥特别重要的作用,而将该手术推迟至分娩后可能导致母亲死亡。据我们所知,这是关于妊娠期手辅助腹腔镜肾切除术的首例报告。