Gotham Katherine, Bishop Somer L, Brunwasser Steven, Lord Catherine
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee.
Autism Res. 2014 Jun;7(3):381-91. doi: 10.1002/aur.1377. Epub 2014 May 6.
The aim of this study was to examine the association between depressive symptoms and several psychosocial constructs (insight into autism symptoms, rumination, desire for social interaction, and satisfaction with social support) that may play a role in the development or maintenance of depression in verbally fluent adolescents and adults with ASD. Participants included 50 individuals with ASD and verbal IQ ≥ 70, aged 16-35 (sample size varied by measure). Elevated depressive symptoms on the Beck Depression Inventory, 2nd edition (BDI-II), were associated with greater self-perceived, autism-related impairments (n = 48), greater rumination (n = 21), and lower perceived social support (n = 37). Rumination tended to moderate the association between self-perceived autism symptoms and BDI-II scores (n = 21), and was significantly associated with ASD-related insistence on sameness behaviors (n = 18). An unexpected relationship between depressive features and social participation and motivation will need to be clarified by longitudinal research. These and similar findings contribute to our understanding of the phenomenology of depression in ASD, which is critical to the development of practical prevention and treatment.
本研究的目的是考察抑郁症状与几种心理社会结构（对自闭症症状的洞察、沉思、社交互动欲望以及对社会支持的满意度）之间的关联，这些心理社会结构可能在语言流畅的患有自闭症谱系障碍（ASD）的青少年和成年人抑郁症的发展或维持中发挥作用。研究参与者包括50名患有ASD且言语智商≥70、年龄在16 - 35岁之间的个体（样本量因测量指标而异）。贝克抑郁量表第二版（BDI-II）上抑郁症状的升高与更高的自我感知的、与自闭症相关的损伤（n = 48）、更多的沉思（n = 21）以及更低的感知社会支持（n = 37）相关。沉思倾向于调节自我感知的自闭症症状与BDI-II得分之间的关联（n = 21），并且与ASD相关的坚持同一性行为显著相关（n = 18）。抑郁特征与社会参与和动机之间的意外关系需要通过纵向研究来阐明。这些以及类似的发现有助于我们理解ASD中抑郁症的现象学，这对于实际预防和治疗的发展至关重要。
