Lubart E, Segal R, Tryhub N, Sigler E, Leibovitz A
Geriatric Department, Shmuel Harofeh Medical Center, Affiliated with the Sackler Faculty of Medicine, Tel Aviv University, 75300 Beer Yaakov, Israel.
Hematologic Disease Unit, Kaplan Medical Center, 76470 Rehovot, Israel.
J Aging Res. 2014;2014:178298. doi: 10.1155/2014/178298. Epub 2014 Apr 3.
Background/Objectives. Blood transfusion is a critical issue for patients with chronic diseases such as heart failure, chronic kidney disease, and malignancy. However, side effects are not rare. The purpose of the study is to evaluate the frequency of adverse blood transfusion reactions in hospitalized elderly patients during a one-year period. Design/Setting/Participants. Blood transfusion reactions such as fever, chills, dyspnea, and others following blood transfusions in hospitalized geriatric patients during one-year period were examined. Results. 382 blood units (242 patients) were administered during the study period. In 40 (11%) cases, blood transfusion reactions occurred. Fever was the most common reaction in 29 cases (72%), four (10%) had shortness of breath, and 3 (8%) had vomiting and chills each. There were no lethal cases in the 24-hour period following blood transfusions. Conclusion. A relatively low rate of adverse blood transfusion reactions occurred in our geriatric patients. We may speculate that this is related to underreporting of minor symptoms due to the high percentage of demented patients in this population.
背景/目的。输血对于心力衰竭、慢性肾病和恶性肿瘤等慢性病患者而言是一个关键问题。然而,副作用并不罕见。本研究的目的是评估住院老年患者在一年期间发生不良输血反应的频率。设计/地点/参与者。对住院老年患者在一年期间输血后出现的发热、寒战、呼吸困难等输血反应进行了检查。结果。在研究期间共输注了382个单位的血液(涉及242名患者)。其中40例(11%)发生了输血反应。发热是最常见的反应,有29例(72%),4例(10%)出现呼吸急促,3例(8%)分别出现呕吐和寒战。输血后24小时内无致死病例。结论。我们的老年患者中发生不良输血反应的比率相对较低。我们推测这可能与该人群中痴呆患者比例较高导致轻微症状报告不足有关。