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利多卡因丁卡因剥脱术对激光脱毛的效果及副作用

The effects and side effects of lidocaine tetracaine peel off on laser-assisted hair removal.

作者信息

Asilian Ali, Shahmoradi Zabihollah, Mazloomi Rabie, Nilforoushzadeh Mohammad Ali

机构信息

Skin and Stem Cell Research Center, Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.

Skin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Adv Biomed Res. 2014 Mar 31;3:110. doi: 10.4103/2277-9175.129716. eCollection 2014.

Abstract

BACKGROUND

Lidocaine 7%-tetracaine 7% is one of the combinations recently offered for performing laser-assisted hair removal. The aim of this study was to compare the effects of this combination with placebo on the side effects of laser-assisted hair removal.

MATERIALS AND METHODS

This clinical trial was carried out on 110 women who referred to Isfahan Spadana laser clinic for laser-assisted hair removal. Lidocaine 7%-tetracaine 7% was applied on one-half of the face, whereas placebo was applied on the other side to create local anesthesia, and after 30 min, the place was cleaned and investigated for complications (edema, erythema, and pallor); then laser therapy was begun. At the end of the therapy, the patients' pain was estimated using Visual Analog Scale (VAS). The data were analyzed using SPSS software by Chi-square and paired t-tests.

RESULTS

The mean age of patients was 27.74 ± 10.8 years. Average levels of anesthesia at 30 min after using lidocaine 7%-tetracaine 7% and placebo based on VAS were 3.6 ± 1.4 and 8.4 ± 1.5, respectively (P = 0.001). In other words, patients felt less pain by using lidocaine 7%-tetracaine 7%. The frequency of complications in patients was not significantly different between the two groups.

CONCLUSION

Considering the better effect of lidocaine 7%-tetracaine 7% compared to placebo and its minimal side effects, we can use it before performing laser-assisted hair removal.

摘要

背景

7%利多卡因-7%丁卡因是最近用于激光脱毛的组合之一。本研究的目的是比较该组合与安慰剂对激光脱毛副作用的影响。

材料与方法

本临床试验对110名前往伊斯法罕斯帕达纳激光诊所进行激光脱毛的女性进行。在面部一侧涂抹7%利多卡因-7%丁卡因,另一侧涂抹安慰剂以进行局部麻醉,30分钟后,清洁该部位并检查并发症(水肿、红斑和苍白);然后开始激光治疗。治疗结束时,使用视觉模拟量表(VAS)评估患者的疼痛程度。数据使用SPSS软件通过卡方检验和配对t检验进行分析。

结果

患者的平均年龄为27.74±10.8岁。基于VAS,使用7%利多卡因-7%丁卡因和安慰剂后30分钟的平均麻醉水平分别为3.6±1.4和8.4±1.5(P = 0.001)。换句话说,使用7%利多卡因-7%丁卡因的患者疼痛感较轻。两组患者并发症的发生率无显著差异。

结论

考虑到7%利多卡因-7%丁卡因比安慰剂效果更好且副作用最小,我们可以在进行激光脱毛前使用它。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50dd/4009754/ce794e3c7008/ABR-3-110-g001.jpg

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