Ohara K, Yoshida T, Sugahara S, Okumura T, Mitsuhashi S, Kawashima M, Akisada M
Dept. of Radiology, Institute of Clinical Medicine, Univ. of Tsukuba.
Gan No Rinsho. 1989 Nov;35(14):1655-9.
The effects of treatment of a bone metastasis have been studied in 49 patients who survived for more than six months after radiotherapy (RT). Relief from the symptoms reached a rate as high as 91% (85/93 irradiated sites) irrespective of the primary site of the cancer. However, the survival rate and the rate of symptom relief maintenance were statistically higher in those with breast cancer (15 patients, 38 irradiated sites) than in those with a lung cancer (15, 24). The local control rate was dose dependent (TDF). High-dose irradiation, therefore is recommended to achieve a high local control rate for patients with a long life expectancy.
对49例放疗（RT）后存活超过6个月的骨转移患者的治疗效果进行了研究。无论癌症原发部位如何，症状缓解率高达91%（93个照射部位中的85个）。然而，乳腺癌患者（15例，38个照射部位）的生存率和症状缓解维持率在统计学上高于肺癌患者（15例，24个照射部位）。局部控制率与剂量相关（TDF）。因此，对于预期寿命较长的患者，建议采用高剂量照射以实现较高的局部控制率。
