Sierro Nicolas, Battey James N D, Ouadi Sonia, Bakaher Nicolas, Bovet Lucien, Willig Adrian, Goepfert Simon, Peitsch Manuel C, Ivanov Nikolai V
Philip Morris International R&D, Philip Morris Products S.A., 2000 Neuchatel, Switzerland.
1] Philip Morris International R&D, Philip Morris Products S.A., 2000 Neuchatel, Switzerland [2].
Nat Commun. 2014 May 8;5:3833. doi: 10.1038/ncomms4833.
The allotetraploid plant Nicotiana tabacum (common tobacco) is a major crop species and a model organism, for which only very fragmented genomic sequences are currently available. Here we report high-quality draft genomes for three main tobacco varieties. These genomes show both the low divergence of tobacco from its ancestors and microsynteny with other Solanaceae species. We identify over 90,000 gene models and determine the ancestral origin of tobacco mosaic virus and potyvirus disease resistance in tobacco. We anticipate that the draft genomes will strengthen the use of N. tabacum as a versatile model organism for functional genomics and biotechnology applications.
异源四倍体植物烟草（普通烟草）是一种主要的作物物种和模式生物，目前仅有非常碎片化的基因组序列。在此，我们报告了三个主要烟草品种的高质量基因组草图。这些基因组既显示了烟草与其祖先的低差异，也显示了与其他茄科物种的微同线性。我们鉴定出超过90,000个基因模型，并确定了烟草花叶病毒和马铃薯Y病毒在烟草中的抗病性的祖先起源。我们预计这些基因组草图将加强烟草作为功能基因组学和生物技术应用的通用模式生物的使用。
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