Zheng Xia, Deng Yan-Li, Li Qi-Jia, Lu Hua
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Apr;34(4):446-9.
To dynamically assess drug targeting of Yougui Pill (YP) and Zuogui Pill (ZP) using infrared thermography.
In this self-control experiment, five healthy volunteers were recruited. By using infrared thermography 10 to 11 thermal images of different body locations were taken from each participant after they took warm water, YP, ZP, and their dissembled prescriptions at 30, 70, 100, 130, and 160 min, respectively. The heat values in the lower quadrant abdomen, uterus, Du channel, and Shenque (CV8) were statistically analyzed after scanning for 125 times.
Administration of YP and its disassembled prescriptions enhanced the heat value of the locations of the Du channel and Shenque (CV8), but did no enhance the heat value of the lower quadrant abdomen at 30 min. Administration of ZP and its disassembled prescriptions reduced the heat value in the locations of the lower quadrant abdomen, uterus, Du channel, and Shenque (CV8) at each time point.
The drug targeting of ZP and YP focused on the locations of the Du channel and Shenque (CV8), not on the locations of the lower quadrant abdomen or uterus.
采用红外热成像技术动态评估右归丸（YP）和左归丸（ZP）的药物靶向性。
本研究为自身对照实验，招募了5名健康志愿者。在志愿者分别服用温水、YP、ZP及其拆方后，于30、70、100、130和160分钟时，使用红外热成像技术从每位参与者身上获取不同身体部位的10至11张热图像。扫描125次后，对下腹部象限、子宫、督脉和神阙穴（CV8）的热值进行统计分析。
服用YP及其拆方后，督脉和神阙穴（CV8）部位的热值在30分钟时升高，但下腹部象限的热值未升高。服用ZP及其拆方后，在各个时间点下腹部象限、子宫、督脉和神阙穴（CV8）部位的热值均降低。
ZP和YP的药物靶向性集中在督脉和神阙穴（CV8）部位，而非下腹部象限或子宫部位。
