Sano Y, Matsuda K, Minami S, Omachi T, Taniyama H
Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan.
Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido, Japan.
J Comp Pathol. 2014 Jul;151(1):126-9. doi: 10.1016/j.jcpa.2014.02.008. Epub 2014 Mar 11.
A 3-year-old male black-tailed prairie dog (Cynomys iudovicianus) was presented with a dome-shaped cutaneous mass over the left femur. Microscopically, the mass was encapsulated and composed of proliferating spindle cells arranged in haphazard, interlacing bundles. There were vascular structures within the mass and some spindle cells had transitioned from the peripheral regions of the vascular wall. Immunohistochemically, the cells expressed vimentin, α-smooth muscle actin, desmin and heavy caldesmon. Based on these findings, the mass was diagnosed as a cutaneous angioleiomyoma. To the best of our knowledge, this is the first case of cutaneous angioleiomyoma in a black-tailed prairie dog.
一只3岁的雄性黑尾土拨鼠（Cynomys ludovicianus）因左股骨上方出现一个圆顶状皮肤肿物而前来就诊。显微镜下，该肿物有包膜，由呈杂乱交错束状排列的增生梭形细胞组成。肿物内有血管结构，一些梭形细胞已从血管壁的周边区域转变而来。免疫组化显示，这些细胞表达波形蛋白、α-平滑肌肌动蛋白、结蛋白和重钙调蛋白。基于这些发现，该肿物被诊断为皮肤血管平滑肌瘤。据我们所知，这是黑尾土拨鼠中首例皮肤血管平滑肌瘤病例。
