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猕猴垂体前叶远侧部中P物质免疫反应性神经纤维

Substance P-immunoreactive nerve fibres in the pars distalis of the anterior pituitary of macaques.

作者信息

Ju G, Liu S J

机构信息

Department of Neurobiology, Fourth Military Medical University, Xian, People's Republic of China.

出版信息

J Chem Neuroanat. 1989 Nov-Dec;2(6):349-60.

PMID:2482050
Abstract

The anterior pituitary glands of Macaca mulatta and M. assamensis were stained with antiserum against substance P (SP). A substantial amount of SP-immunoreactive (ir) nerve fibres with numerous varicosities were found in the pars distalis of the anterior pituitary. They were located in the median part of the gland and were distributed mainly in its dorso-posterior region. The great majority of the varicosities were found to be related to the glandular tissue, although some apparently were located along the walls of the blood sinuses. In addition, many SP-ir cells, mostly large and oval, were distributed at the periphery of the gland. In areas where both SP-ir nerve fibres and cells were present, many cells were found to be in close proximity to the nerve fibres.

摘要

用抗P物质(SP)抗血清对恒河猴和阿萨姆猴的垂体前叶进行染色。在垂体前叶远侧部发现大量具有许多膨体的SP免疫反应性(ir)神经纤维。它们位于腺体的中部,主要分布在其后背区域。虽然有些膨体显然位于血窦壁上,但绝大多数膨体与腺组织有关。此外,许多SP-ir细胞,大多为大的椭圆形,分布在腺体周边。在同时存在SP-ir神经纤维和细胞的区域,发现许多细胞与神经纤维紧邻。

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