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重症中暑导致的横纹肌溶解症和急性肾损伤

Rhabdomyolysis and Acute Kidney Injury due to Severe Heat Stroke.

作者信息

Trujillo Máximo H, Fragachán G Carlos

机构信息

Critical Care Department, ICU, Instituto Médico La Floresta (IMLF), Caracas 1060, Venezuela ; Critical Care Department, University Hospital of Caracas, Caracas 1050, Venezuela.

出版信息

Case Rep Crit Care. 2011;2011:951719. doi: 10.1155/2011/951719. Epub 2011 Sep 27.

DOI:10.1155/2011/951719
PMID:24826326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4010049/
Abstract

We present a case of heat stroke (HS) and acute kidney injury (AKI) due to severe rhabdomyolysis in a 14-year-old previously healthy female patient. When she was practicing strenuous exercise she suffered acute seizures and high fever. These symptoms were followed by coma and multiple organ failure (MOF), which included AKI, encephalopathy, fulminant hepatic failure (FHF), and disseminated intravascular coagulation (DIC). The patient was managed in the ICU with renal replacement therapy, ventilatory support, and other vital supporting measures. After three weeks of ICU treatment she made a full recovery.

摘要

我们报告一例14岁既往健康的女性患者因严重横纹肌溶解导致中暑(HS)和急性肾损伤(AKI)的病例。她在进行剧烈运动时突发急性惊厥和高热。随后出现昏迷及多器官功能衰竭(MOF),包括AKI、脑病、暴发性肝衰竭(FHF)和弥散性血管内凝血(DIC)。患者在重症监护病房(ICU)接受了肾脏替代治疗、通气支持及其他重要支持措施。经过3周的ICU治疗,她完全康复。

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本文引用的文献

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Acute kidney injury in the intensive care unit: an update and primer for the intensivist.重症监护病房中的急性肾损伤:重症医师的更新与入门。
Crit Care Med. 2010 Jan;38(1):261-75. doi: 10.1097/CCM.0b013e3181bfb0b5.
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Rhabdomyolysis and acute kidney injury.横纹肌溶解症与急性肾损伤。
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Rhabdomyolysis.横纹肌溶解症
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Mortality of patients with heatstroke admitted to intensive care units during the 2003 heat wave in France: a national multiple-center risk-factor study.2003年法国热浪期间入住重症监护病房的中暑患者死亡率:一项全国多中心危险因素研究。
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Rhabdomyolysis: an evaluation of 475 hospitalized patients.横纹肌溶解症:对475例住院患者的评估
Medicine (Baltimore). 2005 Nov;84(6):377-385. doi: 10.1097/01.md.0000188565.48918.41.
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The "golden hour" for heatstroke treatment.中暑治疗的“黄金一小时”。
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Fulminant liver disease.暴发性肝病
Clin Liver Dis. 2003 May;7(2):331-49, vi. doi: 10.1016/s1089-3261(03)00026-6.
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Serum creatine kinase as predictor of clinical course in rhabdomyolysis: a 5-year intensive care survey.血清肌酸激酶作为横纹肌溶解症临床病程的预测指标:一项为期5年的重症监护调查
Intensive Care Med. 2003 Jul;29(7):1121-5. doi: 10.1007/s00134-003-1800-5. Epub 2003 May 24.