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颈部肌张力障碍的缓解动作(感觉技巧)

Alleviating manoeuvres (sensory tricks) in cervical dystonia.

作者信息

Patel Neepa, Hanfelt John, Marsh Laura, Jankovic Joseph

机构信息

Department of Neurology and Neurotherapeutics, Center for Movement Disorders, University of Texas Southwestern, Dallas, Texas, USA.

Department of Biostatistics and Bioinformatics, Emory University, Atlanta, Georgia, USA.

出版信息

J Neurol Neurosurg Psychiatry. 2014 Aug;85(8):882-4. doi: 10.1136/jnnp-2013-307316. Epub 2014 May 14.

Abstract

BACKGROUND

There is limited information on the phenomenology, clinical characteristics and pathophysiology of alleviating manoeuvres (AM), also called 'sensory tricks' in cervical dystonia (CD).

METHODS

Individual data, collected from 10 sites participating in the Dystonia Coalition (http://clinicaltrials.gov/show/NCT01373424), included description of localisation and phenomenology of AM collected by systematic review of standardised video examinations. Analyses correlated demographic, neurologic, and psychiatric features of CD patients with or without effective AM.

RESULTS

Of 154 people studied, 138 (89.6%) used AM, of which 60 (43.4%) reported partial improvement, 55 (39.8%) marked improvement, and 4 (0.03%) no effect on dystonic posture. Light touch, usually to the lower face or neck, was used by >90%. The presence or location of AM did not correlate with the severity of the dystonia.

CONCLUSIONS

In this large and comprehensive study of CD, we found no clinical predictors of effective AM. Further studies of sensorimotor integration in dystonia are needed to better understand the pathophysiology of AM.

摘要

背景

关于缓解动作(AM)的现象学、临床特征及病理生理学的信息有限,缓解动作在颈部肌张力障碍(CD)中也被称为“感觉技巧”。

方法

从参与肌张力障碍联盟(http://clinicaltrials.gov/show/NCT01373424)的10个研究点收集的个体数据,包括通过对标准化视频检查进行系统回顾收集到的缓解动作的定位和现象学描述。分析对比了有或没有有效缓解动作的颈部肌张力障碍患者的人口统计学、神经学和精神学特征。

结果

在154名研究对象中,138名(89.6%)使用了缓解动作,其中60名(43.4%)报告肌张力障碍姿势有部分改善,55名(39.8%)有显著改善,4名(0.03%)无改善。超过90%的人使用轻触,通常是触摸下脸部或颈部。缓解动作的存在或位置与肌张力障碍的严重程度无关。

结论

在这项关于颈部肌张力障碍的大型综合性研究中,我们未发现有效缓解动作的临床预测因素。需要对肌张力障碍中的感觉运动整合进行进一步研究,以更好地理解缓解动作的病理生理学机制。

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