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扭转痉挛的技巧:有序复杂性。

Tricks in dystonia: ordering the complexity.

机构信息

Human Motor Control, National Institutes of Health, Bethesda, Maryland, USA.

National Institutes of Health, Bethesda, Maryland, USA.

出版信息

J Neurol Neurosurg Psychiatry. 2014 Sep;85(9):987-93. doi: 10.1136/jnnp-2013-306971. Epub 2014 Jan 31.

Abstract

Sensory tricks are various manoeuvres that can ameliorate dystonia. Common characteristics are well known, but their variety is wide, sensory stimulation is not necessarily the critical feature, and their physiology is unknown. To enumerate the various forms of sensory tricks and describe their nature, research findings and theories that may elucidate their neurophysiologic mechanism, we reviewed the literature pertaining to sensory tricks, including variants like motor tricks, imaginary tricks, forcible tricks and reverse sensory tricks. On the basis of this information, we propose a new classification of sensory tricks to include its variants. We highlight neurophysiologic evidence suggesting that sensory tricks work by decreasing abnormal facilitation. We tie this with established dystonia pathogenesis and postulate that sensory tricks decrease abnormally increased facilitation to inhibition ratios in the dystonic brain. It appears worthwhile for patients to search for possible sensory tricks.

摘要

感觉技巧是多种可以改善肌张力障碍的手法。常见的特征广为人知,但它们的形式多种多样,感觉刺激不一定是关键特征,其生理学机制也不清楚。为了列举各种形式的感觉技巧并描述其性质、可能阐明其神经生理机制的研究结果和理论,我们回顾了与感觉技巧相关的文献,包括运动技巧、想象技巧、强制技巧和反向感觉技巧等变体。在此基础上,我们提出了一种新的感觉技巧分类,包括其变体。我们强调了神经生理证据表明感觉技巧通过降低异常的易化起作用。我们将这与已建立的肌张力障碍发病机制联系起来,并假设感觉技巧降低了痉挛脑异常增加的易化与抑制比率。对于患者来说,寻找可能的感觉技巧似乎是值得的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/799f/4747630/d4bf4ed8b2b0/nihms756330f1.jpg

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