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参加“启智计划”的城市少数族裔儿童心血管疾病风险因素升高。

Cardiovascular disease risk factors are elevated in urban minority children enrolled in head start.

作者信息

Brogan Kathryn, Danford Cynthia, Yeh Yulyu, Jen Kai-Lin Catherine

机构信息

1 Department of Dietetics and Nutrition, Florida International University , Miami, FL.

出版信息

Child Obes. 2014 Jun;10(3):207-13. doi: 10.1089/chi.2013.0146. Epub 2014 May 14.

Abstract

BACKGROUND

The prevalence of obesity and overweight persists in the preschool population, despite some prevention and treatment advances, particularly in minorities. Investigating the prevalence of dyslipidemia and the effect of family health may also guide the focus of intervention efforts.

METHODS

Anthropometric data were collected from urban minority preschool children (n=161; 42% female) enrolled in USDA Head Start. Blood was collected by finger prick and analyzed with the Cholestech LDX Analyzer (Cholestech Corporation, Hayward, CA). Caregivers provided a self-reported family health history for cardiovascular diseases (CVDs).

RESULTS

By BMI percentile, 8% of the children were underweight (UW), 54% healthy weight (HW), 10% overweight (OW), and 28% obese (OB). One of every 5 children had borderline or high-risk levels for total cholesterol (TC), high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides based on the National Cholesterol Education Program categories. In OW/OB children only, BMI was positively correlated with TC (r(61)=0.428; p=0.001) and LDL (r(58)=0.395; p=0.005). Child BMI was also associated with family comorbid diseases (r(159)=0.177; p=0.025). UW/HW children with a family history of CVD had significantly higher LDL than UW/HW children without a family history of CVD (p=0.001). Step-wise regression analysis revealed that BMI (p=0.005) plus family history of heart attack (p=0.018) were significant predictors of blood TC levels.

CONCLUSION

Continued efforts to treat and prevent elevated weight are urgently needed for minority preschoolers. Attention to CVD screening may be an important target in school, community, and healthcare arenas for minority populations regardless of weight status.

摘要

背景

尽管在预防和治疗方面取得了一些进展,尤其是在少数族裔中,但学龄前儿童肥胖和超重的患病率仍然居高不下。调查血脂异常的患病率以及家庭健康的影响也可能指导干预措施的重点。

方法

收集了参加美国农业部“启智计划”的城市少数族裔学龄前儿童(n = 161;42%为女性)的人体测量数据。通过手指采血,并使用Cholestech LDX分析仪(Cholestech公司,加利福尼亚州海沃德)进行分析。照顾者提供了关于心血管疾病(CVD)的自我报告家族健康史。

结果

根据BMI百分位数,8%的儿童体重过轻(UW),54%体重正常(HW),10%超重(OW),28%肥胖(OB)。根据国家胆固醇教育计划的分类,每5名儿童中就有1名总胆固醇(TC)、高密度脂蛋白(HDL)胆固醇、低密度脂蛋白(LDL)胆固醇和甘油三酯处于临界或高危水平。仅在超重/肥胖儿童中,BMI与TC呈正相关(r(61)=0.428;p = 0.001)和LDL呈正相关(r(58)=0.395;p = 0.005)。儿童BMI也与家族共病有关(r(159)=0.177;p = 0.025)。有心血管疾病家族史的体重过轻/体重正常儿童的LDL显著高于没有心血管疾病家族史的体重过轻/体重正常儿童(p = 0.001)。逐步回归分析显示,BMI(p = 0.005)加上心脏病发作家族史(p = 0.018)是血液TC水平的重要预测因素。

结论

少数族裔学龄前儿童迫切需要继续努力治疗和预防体重升高。无论体重状况如何,关注心血管疾病筛查可能是学校、社区和医疗保健领域针对少数族裔人群的一个重要目标。

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