J Psychoactive Drugs. 2014 Jan-Mar;46(1):3-10. doi: 10.1080/02791072.2014.873684.
Since the discovery of its psychedelic properties in 1943, lysergic acid diethylamide (LSD) has been explored by psychiatric/therapeutic researchers, military/intelligence agencies, and a significant portion of the general population. Promising early research was halted by LSD's placement as a Schedule I drug in the early 1970s. The U.S. Army and CIA dropped their research after finding it unreliable for their purposes. NSDUH estimates that more than 22 million (9.1% of the population) have used LSD at least once in their lives. Recently, researchers have been investigating the therapeutic use of LSD and other psychedelics for end-of-life anxiety, post-traumatic stress disorder (PTSD), cancer, and addiction treatment. Adverse psychedelic reactions can be managed using talkdown techniques developed and in use since the 1960s.
自 1943 年发现其迷幻特性以来，LSD（麦角酸二乙基酰胺）一直受到精神科/治疗研究人员、军事/情报机构以及相当一部分普通民众的探索。由于 LSD 在 20 世纪 70 年代初被列为附表 I 药物，早期有希望的研究工作被停止。美国陆军和中央情报局在发现 LSD 对他们的目的不可靠后，放弃了他们的研究。NSDUH 估计，超过 2200 万人（占人口的 9.1%）一生中至少使用过一次 LSD。最近，研究人员一直在调查 LSD 和其他迷幻剂在临终焦虑、创伤后应激障碍（PTSD）、癌症和成瘾治疗方面的治疗用途。自 20 世纪 60 年代以来，已经开发并使用了谈话技巧来管理不良的迷幻反应。
