Suzuki K, Fujii M, Ishii Y, Mochizuki F, Suzuki K, Yamagata M, Suzuki H, Moriya Y, Abiko Y, Sakabe T
Nichidai Koko Kagaku. 1989 Jun;15(2):153-6.
Chemosensitivity of human head and neck tumor was evaluated by human tumor clonogenic assay. Among eight of head and neck tumors seven squamous cell carcinomas such as tongue, gingiva, maxillary sinus, pharynx and one malignant fibrous histiocytoma (MFH) of maxillary sinus and four anti-cancer agents BLM, CDDP, 5-FU and MMC were used. Five of eight tumors were succeeded to evaluate the sensitivity. Positive rates except MFH were BLM 100% (3/3), CDDP 25% (1/4), 5-FU 33% (1/3). These results are similar to recent clinical experiments except CDDP.
通过人肿瘤克隆形成试验评估人头颈肿瘤的化学敏感性。在8例头颈肿瘤中，有7例鳞状细胞癌，如舌癌、牙龈癌、上颌窦癌、咽癌，以及1例上颌窦恶性纤维组织细胞瘤（MFH），使用了4种抗癌药物，即博来霉素（BLM）、顺铂（CDDP）、5-氟尿嘧啶（5-FU）和丝裂霉素（MMC）。8例肿瘤中有5例成功评估了敏感性。除MFH外，阳性率分别为：BLM 100%（3/3）、CDDP 25%（1/4）、5-FU 33%（1/3）。除顺铂外，这些结果与近期的临床实验相似。
