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亚临床乳糜泻与麸质敏感性。

Subclinical celiac disease and gluten sensitivity.

作者信息

Rostami Nejad Mohammad, Hogg-Kollars Sabine, Ishaq Sauid, Rostami Kamran

机构信息

Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

School of Immunity and Infection, University of Birmingham, UK.

出版信息

Gastroenterol Hepatol Bed Bench. 2011 Summer;4(3):102-8.

Abstract

Atypical presentation is the most common form of celiac disease (CD). Although the terminologies like latent, silent and potential have expressed different aspects of clinical and pathological behaviour of CD, they also have contributed in some extent to confusion between clinicians and patients due to the multiple definitions and uncertainty around them. In the light of new advances and the discovery of entities such as non-celiac gluten sensitivity, using subclinical instead of silent and atypical instead of potential/latent may simplify the understanding behind the clinical behaviour of atypical CD. The evidence behind a lower threshold for starting a gluten free diet (GFD) in non-celiac gluten sensitive patients would strongly support applying a GFD treatment strategy in any forms of CD.

摘要

非典型表现是乳糜泻(CD)最常见的形式。尽管诸如隐匿性、无症状性和潜在性等术语表达了CD临床和病理行为的不同方面,但由于其多种定义以及围绕它们的不确定性,在一定程度上也造成了临床医生和患者之间的困惑。鉴于新的进展以及非乳糜泻性麸质敏感等实体的发现,使用亚临床型而非无症状性,以及非典型而非潜在性/隐匿性,可能会简化对非典型CD临床行为背后机制的理解。在非乳糜泻性麸质敏感患者中采用较低门槛启动无麸质饮食(GFD)的证据,将有力支持对任何形式的CD应用GFD治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e445/4017418/41968dcdac5b/GHFBB-4-102-g001.jpg

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