Dietrich R B, Bradley W G
Department of Radiological Sciences, University of California, Los Angeles 90024.
Semin Ultrasound CT MR. 1988 Jun;9(3):192-200.
The unique ability of MR to demonstrate both normal and abnormal white matter maturation with a high degree of sensitivity makes it an indispensable tool with which to evaluate children with clinical developmental delay or suspected dysmyelinating processes. Because the noninvasive nature of MRI allows sequential studies to be performed without additional risk to the patient, it offers an unprecedented opportunity to study the process of myelination in normal infants, developmentally delayed infants and to better understand the dysmyelinating disorders, a relatively rare, poorly understood group of diseases.
磁共振成像（MR）以高度敏感性显示正常和异常白质成熟的独特能力，使其成为评估临床发育迟缓或疑似脱髓鞘过程患儿不可或缺的工具。由于MRI的非侵入性允许在不给患者带来额外风险的情况下进行系列研究，它为研究正常婴儿、发育迟缓婴儿的髓鞘形成过程以及更好地理解脱髓鞘疾病（这是一组相对罕见且了解甚少的疾病）提供了前所未有的机会。
