Grodd W
Department of Neuroradiology, University of Tuebingen, Germany.
Curr Opin Neurol Neurosurg. 1993 Jun;6(3):393-7.
Magnetic resonance imaging allows a noninvasive assessment of myelination during normal brain maturation as well as the detection of genetically determined and acquired diseases that affect the synthesis and maintenance of myelin. If this high sensitivity of magnetic resonance imaging for white matter changes is completed by adequate clinical and biochemical information, a unique diagnostic tool is available to gain new insights in the formation of myelin and pathogenesis of myelin disorders.
磁共振成像能够在正常脑成熟过程中对髓鞘形成进行无创评估，还能检测影响髓鞘合成与维持的遗传性和后天性疾病。如果磁共振成像对白质变化的这种高敏感性能辅以充分的临床和生化信息，那么就可利用这一独特的诊断工具来深入了解髓鞘形成及髓鞘疾病的发病机制。
